Alcoholic Hepatitis Therapeutics Market (Treatment: Corticosteroids, Hemorrheologic Agents, Anabolic Steroids, and Others; Application: Mild and Severe/Chronic; and Distribution Channel: Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies) - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2020 - 2030

Description

Increasing Knowledge Pertaining to Pathophysiology Coupled with Entry of New Treatment Alternatives to Aid Market Growth

The number of individuals suffering from alcoholic liver diseases has witnessed exponential growth over the past two decades and as per current trends, numbers are expected to further grow at a rapid pace. Of various alcoholic liver diseases, alcoholic hepatitis has considerably higher mortality and morbidity rate. In addition, the financial and healthcare burden caused due to alcoholic hepatitis continues to move in the upward curve. Over the past decade, a huge amount of research and development activities has been carried out to improve diagnostic care and quality of treatments.

Research and development activities have revealed that modification of gut microbiota and products related to it, including nutritional intervention, increasing steroid sensitivity, lipopolysaccharide, immune modulation, and epigenetic modification of liver damage caused by alcohol are some of the groundbreaking avenues in the alcoholic hepatitis therapeutics market that are expected to offer tremendous promise during the forecast period. At present, with increasing knowledge pertaining to pathophysiology, new treatment alternatives for alcoholic hepatitis are expected to make an entry into the alcoholic hepatitis therapeutics market.

At the back of these factors, along with growing investments for R&D activities, the global alcoholic hepatitis therapeutics market is expected to reach ~US$ 1.2 Bn by the end of 2030.

High Prevalence of Alcoholic Liver Diseases Worldwide to Fuel Market Growth

The global burden of alcoholic related diseases continues to grow at a rampant pace. According to the World Health Organization, nearly half a million deaths were reported in 2016 that were linked to alcohol-related cirrhosis. At present, companies in the alcoholic hepatitis therapeutics market are primarily focusing on attaining future therapeutic targets by investing in drug development and research activities. The socioeconomic status of different regions of the world is another major factor that has played a key role in dictating the prevalence of alcohol-related digestive diseases.

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Some of the most extensively used treatment alternatives available in the alcoholic hepatitis therapeutics market include pentoxifylline, nutritional therapy, anabolic steroids, and hemorheological agents. Advancements in technology and basic sciences have increased the overall understanding of the pathogenesis of alcoholic liver diseases due to which, the prospects of the alcoholic hepatitis therapeutics market are staring at a bright future. One of the most widely used therapy for alcoholic hepatitis is enteral nutrition and abstinence. Although anabolic steroids are available as an effective treatment option, the adoption of the same is largely hindered due to the side effects.

Research Activities Likely to Stall amid COVID-19 Pandemic, Drug Development to Continue

The advent of the novel COVID-19 pandemic has played a critical role in influencing the overall operations across the healthcare sector. While the pressure remains high to discover a vaccine or drug to treat the novel coronavirus, research activities pertaining to the development of alcoholic hepatitis therapeutics are likely to take a hit amid the ongoing health crisis. Investments are likely to delay along with potential delays in the development of new drugs and therapies. While the market in the first quarter of 2020 was largely affected by the lockdown imposed by the Chinese Government, the second and third quarters are expected to witness considerable bottlenecks across the supply chain due to restrictions on cross-border trade and transportation.

The global alcoholic hepatitis therapeutics market is expected to witness slower growth compared to the growth in 2019. However, as governments around the world gradually ease down lockdown regulations, the alcoholic hepatitis therapeutics market is likely to witness considerable activity toward the last quarter of 2020.

Analysts’ Viewpoint

The global alcoholic hepatitis therapeutics market is expected to grow at a healthy CAGR of ~6% during the forecast period. The market growth can be primarily attributed to the high prevalence of alcohol-related diseases worldwide, emphasis on the development of new therapies, and consistent growth in the number of research and development projects, among others. Market players are anticipated to focus on research activities and collaborate with small- and medium-sized market participants in different regions to expand their presence in the current market landscape. While the COVID-19 pandemic is projected to disrupt operations, product diversification should remain an area of interest.

Alcoholic Hepatitis Therapeutics Market: Overview

Alcoholic hepatitis is an inflammatory condition of the liver caused by high alcohol consumption over an extended period. It is also aggravated by binge drinking and ongoing alcohol use. If a person does not stop alcohol consumption, it can lead to additional health problems, such as cirrhosis, excessive bleeding, or even liver failure.

Symptoms of alcoholic hepatitis include swollen liver, vomiting, nausea, and abdominal pain

The global alcoholic hepatitis therapeutics market has experienced significant growth in the last decade due to rise in prevalence of alcoholic liver diseases and promising drug pipeline & approvals

Different types of therapeutics are used in treatment of alcoholic hepatitis, including corticosteroids, hemorrheologic agents, anabolic steroids, others. Corticosteroids is most commonly used in the treatment of alcoholic hepatitis.

Rise in prevalence of alcoholic liver diseases drives demand for alcoholic hepatitis therapeutics. The most prevalent types of alcoholic liver disease are fatty liver, alcoholic hepatitis, and cirrhosis. The rate of mortality in severe cases is about 50%. If high consumption of alcohol continues, about 40% of patients with alcoholic hepatitis is likely to develop cirrhosis. According to a recent study, around 22,246 people die due to alcoholic liver diseases every year. Of these, 5,786 people are aged between 45 and 54 and 8,126 people between 55 and 64.

Rich product pipeline and recent approval of drugs to treat alcoholic hepatitis are expected to drive the global alcoholic hepatitis therapeutics market during the forecast period. Gilead Sciences, Inc. has one innovative product i.e., Selonsertib (GS-4997), in pipeline (phase 2) for treatment of alcoholic hepatitis. Additionally, rise in alcohol consumption in developed countries such as the U.S. and countries in Europe is likely to increase number of patients with alcoholic hepatitis. In the U.S., consumption of pure alcohol per capita is 8.7 liters.

Market Segmentation: Alcoholic Hepatitis Therapeutics Market

In terms of treatment, the global alcoholic hepatitis therapeutics market has been divided into corticosteroids, hemorrheologic agents, anabolic steroids, and others. The corticosteroid segment is likely to dominate the global alcoholic hepatitis therapeutics market during the forecast period.

Based on application, the global alcoholic hepatitis therapeutics market has been classified into mild and severe/chronic

In terms of distribution channel, the global alcoholic hepatitis therapeutics market has been categorized into hospital pharmacies, retail pharmacies, and online pharmacies. The hospital pharmacies segment dominated the global alcoholic hepatitis therapeutics market in terms of revenue in 2019.

Each of the segments has been analyzed in detail for market trends, recent trends, and developments, drivers, restraints, opportunities, and useful insights. The report provides current and expected revenue (US$ Mn) for each of these segments from 2018 to 2030, considering 2019 as the base year. The compound annual growth rate (CAGR %) has been provided for each segment and market from 2020 to 2030, along with market size estimations.

Regional Overview: Alcoholic Hepatitis Therapeutics Market

In terms of region, the global alcoholic hepatitis therapeutics market has been segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. The regions have been divided into major countries and sub-regions.

The current and expected market revenue (US$ Mn) of these regional markets and their major countries have been provided in the report from 2018 to 2030, with their CAGRs from 2020 to 2030

The study also offers a list of recommendations, highlights, and useful insights of the global alcoholic hepatitis therapeutics market, which would help new companies willing to enter the market and existing companies to increase market shares, and help in the decision-making process

Major Players

The alcoholic hepatitis therapeutics market report concludes with the company profiles section, which includes key information about major players in the global alcoholic hepatitis therapeutics market

Leading players analyzed in the alcoholic hepatitis therapeutics market report include 

  • Gilead Sciences, Inc.
  • Sanofi
  • Generon Pharmaceutical Technology (Shanghai) Co., Ltd
  • Immuron Ltd.
  • Intercept Pharmaceuticals, Inc.

Each of these players has been profiled in the alcoholic hepatitis therapeutics market report based on parameters such as company overview, financial overview, business strategies, product portfolio, business segments, and recent developments

Key Questions Answered in Alcoholic Hepatitis Therapeutics Market Report

  • What is the sales/revenue generated by alcoholic hepatitis therapeutics across all regions during the forecast period?
  • What are the opportunities in the global alcoholic hepatitis therapeutics market?
  • What are the major drivers, restraints, opportunities, and threats in the market?
  • Which regional market is set to expand at the fastest CAGR during the forecast period?
  • Which treatment segment is expected to generate the highest revenue globally in 2030? Which segment is projected to expand at the highest CAGR during the forecast period?
  • What are the market positions of different companies operating in the global market?

Alcoholic Hepatitis Therapeutics Market – Segmentation

Treatment

  • Corticosteroids
  • Hemorrheologic Agents
  • Anabolic Steroids
  • Others

Application

  • Mild
  • Severe/Chronic

Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

Region

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East & Africa

TABLE OF CONTENT

1. Preface

    1.1. Report Scope and Market Segmentation 

    1.2. Research Highlights

2. Assumptions and Research Methodology 

    2.1. Assumptions

    2.2. Research Methodology

3. Executive Summary

    3.1. Global Alcoholic Hepatitis Therapeutics Market Snapshot

4. Market Overview

    4.1. Product Overview

    4.2. Market Dynamics

    4.3. Drivers and Restraints Snapshot Analysis

        4.3.1. Drivers

        4.3.2. Restraints 

        4.3.3. Opportunities 

        4.3.4. Key Trends

    4.4. Global Alcoholic Hepatitis Therapeutics Market Revenue Projection

    4.5. Global Alcoholic Hepatitis Therapeutics Market Outlook

5. Market Outlook

    5.1. COVID-19 Pandemic Impact on Global Alcoholic Hepatitis Therapeutics Industry

    5.2. Regulatory Scenario, by Region/globally

    5.3. Health Care Overview

    5.4. Pipeline Analysis

    5.5. Epidemiology of Alcoholic Liver Diseases

    5.6. Overview of Alcoholic Hepatitis

6. Global Alcoholic Hepatitis Therapeutics Market Analysis, by Treatment

    6.1. Introduction 

    6.2. Global Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Treatment

    6.3. Global Alcoholic Hepatitis Therapeutics Market Forecast, by Treatment

        6.3.1. Corticosteroids

        6.3.2. Hemorrheologic Agents

        6.3.3. Anabolic Steroids

        6.3.4. Others

    6.4. Global Alcoholic Hepatitis Therapeutics Market Analysis, by Treatment

7. Global Alcoholic Hepatitis Therapeutics Market Analysis, by Application

    7.1. Introduction 

    7.2. Global Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Application

    7.3. Global Alcoholic Hepatitis Therapeutics Market Forecast, by Application

        7.3.1. Mild

        7.3.2. Severe/Chronic

    7.4. Global Alcoholic Hepatitis Therapeutics Market Analysis, by Application

8. Global Alcoholic Hepatitis Therapeutics Market Analysis, by Distribution Channel

    8.1. Introduction 

    8.2. Global Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Distribution Channel

    8.3. Global Alcoholic Hepatitis Therapeutics Market Forecast, by Distribution Channel

        8.3.1. Hospital Pharmacies

        8.3.2. Retail Pharmacies

        8.3.3. Online Pharmacies

    8.4. Global Alcoholic Hepatitis Therapeutics Market Analysis, by Distribution Channel

9. Global Alcoholic Hepatitis Therapeutics Market Analysis, by Region

    9.1. Global Alcoholic Hepatitis Therapeutics Market Scenario, by Country

    9.2. Global Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Region 

    9.3. Global Alcoholic Hepatitis Therapeutics Market Forecast, by Region

        9.3.1. North America

        9.3.2. Europe

        9.3.3. Asia Pacific

        9.3.4. Latin America

        9.3.5. Middle East & Africa

10. North America Alcoholic Hepatitis Therapeutics Market Analysis

    10.1. North America Alcoholic Hepatitis Therapeutics Market Analysis

    10.2. North America Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Treatment

    10.3. North America Alcoholic Hepatitis Therapeutics Market Forecast, by Treatment

        10.3.1. Corticosteroids

        10.3.2. Hemorrheologic Agents

        10.3.3. Anabolic Steroids

        10.3.4. Others

    10.4. North America Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Application

    10.5. North America Alcoholic Hepatitis Therapeutics Market Forecast, by Application

        10.5.1. Mild

        10.5.2. Severe/Chronic

    10.6. North America Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Distribution Channel

    10.7. North America Alcoholic Hepatitis Therapeutics Market Forecast, by Distribution Channel

        10.7.1. Hospital Pharmacies

        10.7.2. Retail Pharmacies

        10.7.3. Online Pharmacies

    10.8. North America Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Country

    10.9. North America Alcoholic Hepatitis Therapeutics Market Forecast, by Country

        10.9.1. U.S.

        10.9.2. Canada

11. Europe Alcoholic Hepatitis Therapeutics Market Analysis

    11.1. Europe Alcoholic Hepatitis Therapeutics Market Analysis

    11.2. Europe Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Treatment

    11.3. Europe Alcoholic Hepatitis Therapeutics Market Forecast, by Treatment

        11.3.1. Corticosteroids

        11.3.2. Hemorrheologic Agents

        11.3.3. Anabolic Steroids

        11.3.4. Others

    11.4. Europe Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Application

    11.5. Europe Alcoholic Hepatitis Therapeutics Market Forecast, by Application

        11.5.1. Mild

        11.5.2. Severe/Chronic

    11.6. Europe Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Distribution Channel

    11.7. Europe Alcoholic Hepatitis Therapeutics Market Forecast, by Distribution Channel

        11.7.1. Hospital Pharmacies

        11.7.2. Retail Pharmacies

        11.7.3. Online Pharmacies

    11.8. Europe Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Country/Sub-region

    11.9. Europe Alcoholic Hepatitis Therapeutics Market Forecast, by Country/Sub-region

        11.9.1. U.K.

        11.9.2. Germany

        11.9.3. France

        11.9.4. Spain

        11.9.5. Italy

        11.9.6. Rest of Europe

12. Asia Pacific Alcoholic Hepatitis Therapeutics Market Analysis

    12.1. Asia Pacific Alcoholic Hepatitis Therapeutics Market Analysis

    12.2. Asia Pacific Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Treatment

    12.3. Asia Pacific Alcoholic Hepatitis Therapeutics Market Forecast, by Treatment

        12.3.1. Corticosteroids

        12.3.2. Hemorrheologic Agents

        12.3.3. Anabolic Steroids

        12.3.4. Others

    12.4. Asia Pacific Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Application

    12.5. Asia Pacific Alcoholic Hepatitis Therapeutics Market Forecast, by Application

        12.5.1. Mild

        12.5.2. Severe/Chronic

    12.6. Asia Pacific Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Distribution Channel

    12.7. Asia Pacific Alcoholic Hepatitis Therapeutics Market Forecast, by Distribution Channel

        12.7.1. Hospital Pharmacies

        12.7.2. Retail Pharmacies

        12.7.3. Online Pharmacies

    12.8. Asia Pacific Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Country/Sub-region

    12.9. Asia Pacific Alcoholic Hepatitis Therapeutics Market Forecast, by Country/Sub-region

        12.9.1. Australia & New Zealand

        12.9.2. Japan

        12.9.3. China

        12.9.4. India

        12.9.5. Rest of Asia Pacific

13. Latin America Alcoholic Hepatitis Therapeutics Market Analysis

    13.1. Latin America Alcoholic Hepatitis Therapeutics Market Analysis

    13.2. Latin America Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Treatment

    13.3. Latin America Alcoholic Hepatitis Therapeutics Market Forecast, by Treatment

        13.3.1. Corticosteroids

        13.3.2. Hemorrheologic Agents

        13.3.3. Anabolic Steroids

        13.3.4. Others

    13.4. Latin America Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Application

    13.5. Latin America Alcoholic Hepatitis Therapeutics Market Forecast, by Application

        13.5.1. Mild

        13.5.2. Severe/Chronic

    13.6. Latin America Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Distribution Channel

    13.7. Latin America Alcoholic Hepatitis Therapeutics Market Forecast, by Distribution Channel

        13.7.1. Hospital Pharmacies

        13.7.2. Retail Pharmacies

        13.7.3. Online Pharmacies

    13.8. Latin America Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Country/Sub-region

    13.9. Latin America Alcoholic Hepatitis Therapeutics Market Forecast, by Country/Sub-region

        13.9.1. Brazil

        13.9.2. Mexico

        13.9.3. Rest of Latin America

14. Middle East & Africa Alcoholic Hepatitis Therapeutics Market Analysis

    14.1. Middle East & Africa Alcoholic Hepatitis Therapeutics Market Analysis

    14.2. Middle East & Africa Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Treatment

    14.3. Middle East & Africa Alcoholic Hepatitis Therapeutics Market Forecast, by Treatment

        14.3.1. Corticosteroids

        14.3.2. Hemorrheologic Agents

        14.3.3. Anabolic Steroids

        14.3.4. Others

    14.4. Middle East & Africa Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Application

    14.5. Middle East & Africa Alcoholic Hepatitis Therapeutics Market Forecast, by Application

        14.5.1. Mild

        14.5.2. Severe/Chronic

    14.6. Middle East & Africa Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Distribution Channel

    14.7. Middle East & Africa Alcoholic Hepatitis Therapeutics Market Forecast, by Distribution Channel

        14.7.1. Hospital Pharmacies

        14.7.2. Retail Pharmacies

        14.7.3. Online Pharmacies

    14.8. Middle East & Africa Alcoholic Hepatitis Therapeutics Market Value Share and Attractiveness Analysis, by Country/Sub-region

    14.9. Middle East & Africa Alcoholic Hepatitis Therapeutics Market Forecast, by Country/Sub-region

        14.9.1. GCC Countries

        14.9.2. South Africa

        14.9.3. Rest of Middle East & Africa

15. Competitive Landscape

    15.1. Company Profile

        15.1.1. Gilead Sciences, Inc. 

            15.1.1.1. Company Overview (HQ, Business Segments, Employee Strength)

            15.1.1.2. Financial Overview

            15.1.1.3. Product Portfolio

            15.1.1.4. SWOT Analysis

            15.1.1.5. Strategic Overview

        15.1.2. Sanofi

            15.1.2.1. Company Overview (HQ, Business Segments, Employee Strength)

            15.1.2.2. Financial Overview

            15.1.2.3. Product Portfolio

            15.1.2.4. SWOT Analysis

            15.1.2.5. Strategic Overview

        15.1.3. Generon Pharmaceutical Technology (Shanghai) Co., Ltd. 

            15.1.3.1. Company Overview (HQ, Business Segments, Employee Strength)

            15.1.3.2. Financial Overview

            15.1.3.3. Product Portfolio

            15.1.3.4. SWOT Analysis

            15.1.3.5. Strategic Overview

        15.1.4. Immuron Ltd. 

            15.1.4.1. Company Overview (HQ, Business Segments, Employee Strength)

            15.1.4.2. Product Portfolio

            15.1.4.3. SWOT Analysis

            15.1.4.4. Strategic Overview

        15.1.5. Intercept Pharmaceuticals, Inc. 

            15.1.5.1. Company Overview (HQ, Business Segments, Employee Strength)

            15.1.5.2. Financial Overview

            15.1.5.3. Product Portfolio

            15.1.5.4. SWOT Analysis

            15.1.5.5. Strategic Overview

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