Rising Global Burden of Hypertension Provides Impetus for Development of New Drugs
Hypertension is a critical health condition that can lead to cardiovascular diseases, renal failure, stroke, and even death. According to the World Health Organization, 1.13 billion individuals worldwide had hypertension in 2018, of which two-third resided in low income and developing countries. Over the past decade, the global burden of hypertension has increased, primarily driven by a significant rise in population, lifestyle changes, and increase in the geriatric population worldwide. In the current scenario, hypertension is effectively controlled in less than 20% of the patients across the world, which means there is a mounting demand for antihypertensive drugs, particularly in developing regions.
Over the past few decades, a significant amount of research has been undertaken for the discovery of new, effective, and novel antihypertensive drugs. Despite significant advancements in genomics, clinical applications of these relatively recent developments in the antihypertensive drugs market landscape remain far-fetched. Drug manufacturers continue to invest significant resources toward the discovery of blockbuster antihypertensive drugs. However, to achieve this goal, stakeholders in the current antihypertensive drugs market are likely to adopt a cross-sector approach that will focus on several areas, including data, digital, population sciences, etc.
The global antihypertensive drugs market is expected to reach a market value of ~US$ 33.9 Bn by the end of 2027.
Adoption of Combination Therapies to Gain Significant Momentum
Research and development have taken the center stage in the current antihypertensive drugs market. Established and upcoming players in the current market landscape are increasingly focusing on the formulation of effective combination therapies. Uptake of combination therapies is a trend that is projected to gain significant momentum during the forecast period (2019-2027).
Focus on combination therapies in the antihypertensive drugs market is likely to increase to achieve therapeutic goals. Furthermore, recent guidelines related to hypertension management suggest that combination therapy, in which two or more drugs are combined, is ideal for patients that have systolic blood pressure and patients at a higher cardiovascular risk. In addition, several research activities have revealed that ~25% of patients may require a combination therapy of three antihypertensive drugs to attain the desirable outcome. Combination therapy is expected to be the most prominent medication type. The combination therapy segment of the antihypertensive drugs market is projected to reach a market value of ~ US$ 12.4 Mn and account for a market share of ~43% in 2020.
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Conventionally, a higher dose of monotherapy is required. However, this approach could potentially increase the risk of side effects. These drawbacks of monotherapy have paved the way for other medication types in the global antihypertensive drugs market such as fixed dose combinations and combination therapy. With a market share of ~33%, the fixed dose combinations medication type segment is expected to hold the second-highest market share of the antihypertensive drugs market in 2020.
Companies Focus on R&D to Offer Effective Antihypertensive Drugs
Stakeholders in the global antihypertensive drug market are increasing their efforts toward the discovery of new drugs to manage high blood pressure. Research activities are focused on the discovery of new combination drugs. For instance, clinical trials have revealed that new combination therapy could revolutionize hypertension management worldwide. A team of researchers from the George Institute for Global Health tested the efficacy and safety of an innovative combination drug to deal with hypertension and elevated blood pressure. The new drug, which was declared safe after a series of clinical trials, is a combination of three drugs - amlodipine, chlorthalidone, and telmisartan. Several other drug manufacturers are focused on receiving approval from the FDA for hypertension medicine. For instance, in December 2018, Alembic Pharmaceuticals announced that the company received approval from the US FDA for a new hypertension medicine.
Hospital pharmacies are expected to be the most sought-after distribution channel. Additionally, ~44% of the total sales of antihypertensive drugs is expected to take place from hospital pharmacies in 2020. Hospital pharmacies segment is projected to generate a revenue of ~US$ 12.5 Bn in 2020.
Analysts’ Viewpoint
The global antihypertensive drugs market is projected to expand at a CAGR of ~2% during the forecast period. Despite apprehensions among drug manufacturers about the development of new antihypertensive drugs, research and activities are likely to concentrate on improving the effectiveness of combination therapies. The adoption of combination therapies will be the highest, followed by fixed dose combinations. Players operating in the antihypertensive drugs market should focus on the development of cost-effective combination therapies. North America and Europe are expected to be the major regions, in terms of innovations and new drug development, owing to high concentration of top tier market players.
Antihypertensive Drugs Market: Overview
This report analyzes the current scenario and future prospects of the global antihypertensive drugs market. Rise in prevalence of geriatric population is expected to increase at a rapid pace in the next few years. Based on United Nations Report 2017, the geriatric population aged 60 years and above is expected to double by 2050. The number is anticipated to increase from 962 million in 2017 to 2.1 billion by 2050.
Moreover, the geriatric patient pool in developing regions such as Latin America, Asia, and Africa is likely to increase rapidly. Age is a primary risk factor for hypertension. Prevalence of hypertension is comparatively high in the elderly population; approximately 70% of high blood pressure patients are over 60. Additionally, aging increases blood pressure, as elasticity of the arterial system is reduced. All these factors are expected to drive the antihypertensive drugs market in the next few years.
The report provides an elaborate executive summary, which provides a snapshot of various segments of the antihypertensive drugs market. It also provides information and data analysis of the global antihypertensive drugs market with regards to segments based on therapy type, type, medication type, distribution channel, and region.
The overview section of the report provides a detailed qualitative analysis of drivers, restraints, and opportunities that impact the global antihypertensive drugs market
The report includes company profiles, which provide information about their business, product portfolios, and competitive landscape in the antihypertensive drugs market
The report on the global antihypertensive drugs market offers market attractiveness analysis of regions and segments
The last section of the report comprises quantitative and qualitative analysis on market share/position of key players operating in the global antihypertensive drugs market. It analyzes key competitive strategies adopted by major industry players, thereby presenting a thorough understanding of the competitive scenario in the global antihypertensive drugs market.
Antihypertensive Drugs Market: Key Segments
In terms of drug, the antihypertensive drugs market has been segmented into diuretics, angiotensin converting enzyme inhibitors, angiotensin receptor blockers, beta-blockers, vasodilators, calcium channel blockers, renin inhibitors, alpha-blockers, and others. The diuretics segment has been sub-segmented into thiazide diuretic, loop diuretics, and potassium-sparing diuretics. Beta-blockers segment has been sub-segmented into beta-1 selective and intrinsic sympathomimetic.
The angiotensin receptor blockers segment held a major share of the global antihypertensive drugs market in 2018 and the trend is expected to continue during the forecast period
Based on condition, the antihypertensive drugs market has been segregated into primary hypertension and secondary hypertension. The primary hypertension segment accounted for a major market share in 2018; the trend is expected to continue during the forecast period.
In terms of medication type, the antihypertensive drugs market has been categorized into monotherapy, combination therapy, and fixed dose combinations
Based on distribution channel, the global antihypertensive drugs market has been classified into retail pharmacies, hospital pharmacies, online pharmacies, and others. The hospital pharmacies segment of accounted for a major share of the antihypertensive drugs market in 2018.
Market size and forecast for each of these segments have been provided from 2017 to 2027. The CAGR of respective segment has also been provided from 2019 to 2027, considering 2018 as the base year.
Antihypertensive Drugs Market: Regional Outlook
In terms of region, the global antihypertensive drugs market has been divided into North America (U.S. and Canada), Europe (U.K., Germany, Spain, Italy, France, and Rest of Europe), Asia Pacific (China, India, Japan, Australia & New Zealand, and Rest of Asia Pacific), Latin America (Brazil, Mexico, and Rest of Latin America), and Middle East & Africa (GCC Countries, South Africa, and Rest of Middle East & Africa). Each region considered in the market has been further divided into countries/sub-regions.
The antihypertensive drugs market report provides size and forecast for each region and country/sub-region from 2017 to 2027. The CAGR for each of these regions and countries have also been provided for the forecast period from 2019 to 2027. The antihypertensive drugs market study also covers the competitive scenario in these regions.
Companies Covered in Antihypertensive Drugs Market Report
Key players in the global antihypertensive drugs market have been profiled based on attributes such as company overview, product portfolio, financial overview, recent developments, and competitive business strategies
Major companies profiled in the global antihypertensive drugs market report include
Key Questions Answered in Antihypertensive Drugs Market Report
Antihypertensive Drugs Market – Segmentation
Drug
Condition
Medication Type
Distribution Channel
Region
1. Preface
1.1. Market Definition and Scope
1.2. Market Segmentation
1.3. Key Research Objectives
1.4. Research Highlights
2. Assumptions and Research Methodology
3. Executive Summary : Global Antihypertensive Drugs Market
4. Market Overview
4.1. Introduction
4.2. Overview
4.3. Market Dynamics
4.3.1. Drivers
4.3.2. Restraints
4.3.3. Opportunities
4.4. Global Antihypertensive Drugs Market Analysis and Forecast, 2017–2030
4.4.1. Market Revenue Projections (US$ Mn)
5. Market Outlook
5.1. Key Industry Developments
5.2. Regulatory Scenario
5.3. Reimbursement Scenario
5.4. Key Mergers & Acquisitions
5.5. Technological Advancements
6. Global Antihypertensive Drugs Market Value (US$ Mn) Forecast, by Drug
6.1. Introduction & Definition
6.2. Global Antihypertensive Drugs Market Value Forecast, by Drug, 2017–2030
6.2.1. Diuretics
6.2.1.1. Thiazide Diuretics
6.2.1.2. Loop Diuretics
6.2.1.3. Potassium-sparing Diuretics
6.2.2. Angiotensin Converting Enzyme Inhibitors
6.2.3. Angiotensin Receptor Blockers
6.2.4. Beta-blockers
6.2.4.1. Beta-1 Selective
6.2.4.2. Intrinsic Sympathomimetic
6.2.5. Vasodilators
6.2.6. Calcium Channel Blockers
6.2.7. Renin Inhibitors
6.2.8. Alpha-blockers
6.2.9. Others
6.3. Global Antihypertensive Drugs Market Attractiveness, by Drug
7. Global Antihypertensive Drugs Market Value (US$ Mn) Forecast, by Condition
7.1. Introduction & Definition
7.2. Global Antihypertensive Drugs Market Value Forecast, by Condition, 2017–2030
7.2.1. Primary Hypertension
7.2.2. Secondary Hypertension
7.3. Global Antihypertensive Drugs Market Attractiveness, by Condition
8. Global Antihypertensive Drugs Market Value (US$ Mn) Forecast, by Medication Type
8.1. Introduction
8.2. Global Antihypertensive Drugs Market Value Forecast, by Medication Type, 2017–2030
8.2.1. Monotherapy
8.2.2. Combination Therapy
8.2.3. Fixed Dose Combinations
8.3. Global Antihypertensive Drugs Market Attractiveness, by Medication Type
9. Global Antihypertensive Drugs Market Value (US$ Mn) Forecast, by Distribution Channel
9.1. Introduction
9.2. Global Antihypertensive Drugs Market Value Forecast, by Distribution Channel, 2017–2030
9.2.1. Retail Pharmacies
9.2.2. Hospital Pharmacies
9.2.3. Online Pharmacies
9.2.4. Others
9.3. Global Antihypertensive Drugs Market Attractiveness, by Distribution Channel
10. Global Antihypertensive Drugs Market Value (US$ Mn) Forecast, by Region
10.1. Introduction
10.2. Antihypertensive Drugs Market Value Forecast, by Region, 2017–2030
10.2.1. North America
10.2.2. Europe
10.2.3. Asia Pacific
10.2.4. Latin America
10.2.5. Middle East & Africa
10.3. Global Antihypertensive Drugs Market Attractiveness, by Region
11. North America Antihypertensive Drugs Market Analysis and Forecast
11.1. Introduction
11.2. North America Antihypertensive Drugs Market Value Forecast, by Drug, 2017–2030
11.2.1. Diuretics
11.2.1.1. Thiazide Diuretics
11.2.1.2. Loop Diuretics
11.2.1.3. Potassium-sparing Diuretics
11.2.2. Angiotensin Converting Enzyme Inhibitors
11.2.3. Angiotensin Receptor Blockers
11.2.4. Beta-blockers
11.2.4.1. Beta-1 Selective
11.2.4.2. Intrinsic Sympathomimetic
11.2.5. Vasodilators
11.2.6. Calcium Channel Blockers
11.2.7. Renin Inhibitors
11.2.8. Alpha-blockers
11.2.9. Others
11.3. North America Antihypertensive Drugs Market Value Forecast, by Condition, 2017–2030
11.3.1. Primary Hypertension
11.3.2. Secondary Hypertension
11.4. North America Antihypertensive Drugs Market Value Forecast, by Medication Type, 2017–2030
11.4.1. Monotherapy
11.4.2. Combination Therapy
11.4.3. Fixed Dose Combinations
11.4.4. Others
11.5. North America Antihypertensive Drugs Market Value Forecast, by Distribution Channel, 2017–2030
11.5.1. Retail Pharmacies
11.5.2. Hospital Pharmacies
11.5.3. Online Pharmacies
11.5.4. Others
11.6. North America Antihypertensive Drugs Market Value Forecast, by Country, 2017–2030
11.6.1. U.S.
11.6.2. Canada
11.7. North America Antihypertensive Drugs Market Attractiveness Analysis
11.7.1. By Drug
11.7.2. By Condition
11.7.3. By Medication Type
11.7.4. By Distribution Channel
11.7.5. By Country
12. Europe Antihypertensive Drugs Market Analysis and Forecast
12.1. Introduction
12.2. Europe Antihypertensive Drugs Market Value Forecast, by Drug, 2017–2030
12.2.1. Diuretics
12.2.1.1. Thiazide Diuretics
12.2.1.2. Loop Diuretics
12.2.1.3. Potassium-sparing Diuretics
12.2.2. Angiotensin Converting Enzyme Inhibitors
12.2.3. Angiotensin Receptor Blockers
12.2.4. Beta-blockers
12.2.4.1. Beta-1 Selective
12.2.4.2. Intrinsic Sympathomimetic
12.2.5. Vasodilators
12.2.6. Calcium Channel Blockers
12.2.7. Renin Inhibitors
12.2.8. Alpha-blockers
12.2.9. Others
12.3. Europe Antihypertensive Drugs Market Value Forecast, by Condition, 2017–2030
12.3.1. Primary Hypertension
12.3.2. Secondary Hypertension
12.4. Europe Antihypertensive Drugs Market Value Forecast, by Medication Type, 2017–2030
12.4.1. Monotherapy
12.4.2. Combination Therapy
12.4.3. Fixed Dose Combinations
12.4.4. Others
12.5. Europe Antihypertensive Drugs Market Value Forecast, by Distribution Channel, 2017–2030
12.5.1. Retail Pharmacies
12.5.2. Hospital Pharmacies
12.5.3. Online Pharmacies
12.5.4. Others
12.6. Europe Antihypertensive Drugs Market Value Forecast, by Country/Sub-region, 2017–2030
12.6.1. Germany
12.6.2. U.K.
12.6.3. France
12.6.4. Spain
12.6.5. Italy
12.6.6. Rest of Europe
12.7. Europe Antihypertensive Drugs Market Attractiveness Analysis
12.7.1. By Drug
12.7.2. By Condition
12.7.3. By Medication Type
12.7.4. By Distribution Channel
12.7.5. By Country/Sub-region
13. Asia Pacific Antihypertensive Drugs Market Analysis and Forecast
13.1. Introduction
13.2. Asia Pacific Antihypertensive Drugs Market Value Forecast, by Drug, 2017–2030
13.2.1. Diuretics
13.2.1.1. Thiazide Diuretics
13.2.1.2. Loop Diuretics
13.2.1.3. Potassium-sparing Diuretics
13.2.2. Angiotensin Converting Enzyme Inhibitors
13.2.3. Angiotensin Receptor Blockers
13.2.4. Beta-blockers
13.2.4.1. Beta-1 Selective
13.2.4.2. Intrinsic Sympathomimetic
13.2.5. Vasodilators
13.2.6. Calcium Channel Blockers
13.2.7. Renin Inhibitors
13.2.8. Alpha-blockers
13.2.9. Others
13.3. Asia Pacific Antihypertensive Drugs Market Value Forecast, by Condition, 2017–2030
13.3.1. Primary Hypertension
13.3.2. Secondary Hypertension
13.4. Asia Pacific Antihypertensive Drugs Market Value Forecast, by Medication Type, 2017–2030
13.4.1. Monotherapy
13.4.2. Combination Therapy
13.4.3. Fixed Dose Combinations
13.4.4. Others
13.5. Asia Pacific Antihypertensive Drugs Market Value Forecast, by Distribution Channel, 2017–2030
13.5.1. Retail Pharmacies
13.5.2. Hospital Pharmacies
13.5.3. Online Pharmacies
13.5.4. Others
13.6. Asia Pacific Antihypertensive Drugs Market Value Forecast, by Country/Sub-region, 2017–2030
13.6.1. Japan
13.6.2. China
13.6.3. India
13.6.4. Australia & New Zealand
13.6.5. Rest of Asia Pacific
13.7. Asia Pacific Antihypertensive Drugs Market Attractiveness Analysis
13.7.1. By Drug
13.7.2. By Condition
13.7.3. By Medication Type
13.7.4. By Distribution Channel
13.7.5. By Country/Sub-region
14. Latin America Antihypertensive Drugs Market Analysis and Forecast
14.1. Introduction
14.2. Latin America Antihypertensive Drugs Market Value Forecast, by Drug, 2017–2030
14.2.1. Diuretics
14.2.1.1. Thiazide Diuretics
14.2.1.2. Loop Diuretics
14.2.1.3. Potassium-sparing Diuretics
14.2.2. Angiotensin Converting Enzyme Inhibitors
14.2.3. Angiotensin Receptor Blockers
14.2.4. Beta-blockers
14.2.4.1. Beta-1 Selective
14.2.4.2. Intrinsic Sympathomimetic
14.2.5. Vasodilators
14.2.6. Calcium Channel Blockers
14.2.7. Renin Inhibitors
14.2.8. Alpha-blockers
14.2.9. Others
14.3. Latin America Antihypertensive Drugs Market Value Forecast, by Condition, 2017–2030
14.3.1. Primary Hypertension
14.3.2. Secondary Hypertension
14.4. Latin America Antihypertensive Drugs Market Value Forecast, by Medication Type, 2017–2030
14.4.1. Monotherapy
14.4.2. Combination Therapy
14.4.3. Fixed Dose Combinations
14.4.4. Others
14.5. Latin America Antihypertensive Drugs Market Value Forecast, by Distribution Channel, 2017–2030
14.5.1. Retail Pharmacies
14.5.2. Hospital Pharmacies
14.5.3. Online Pharmacies
14.5.4. Others
14.6. Latin America Antihypertensive Drugs Market Value Forecast, by Country/Sub-region, 2017–2030
14.6.1. Brazil
14.6.2. Mexico
14.6.3. Rest of Latin America
14.7. Latin America Antihypertensive Drugs Market Attractiveness Analysis
14.7.1. By Drug
14.7.2. By Condition
14.7.3. By Medication Type
14.7.4. By Distribution Channel
14.7.5. By Country/Sub-region
15. Middle East & Africa Antihypertensive Drugs Market Analysis and Forecast
15.1. Introduction
15.2. Middle East & Africa Antihypertensive Drugs Market Value Forecast, by Drug, 2017–2030
15.2.1. Diuretics
15.2.1.1. Thiazide Diuretics
15.2.1.2. Loop Diuretics
15.2.1.3. Potassium-sparing Diuretics
15.2.2. Angiotensin Converting Enzyme Inhibitors
15.2.3. Angiotensin Receptor Blockers
15.2.4. Beta-blockers
15.2.4.1. Beta-1 Selective
15.2.4.2. Intrinsic Sympathomimetic
15.2.5. Vasodilators
15.2.6. Calcium Channel Blockers
15.2.7. Renin Inhibitors
15.2.8. Alpha-blockers
15.2.9. Others
15.3. Middle East & Africa Antihypertensive Drugs Market Value Forecast, by Condition, 2017–2030
15.3.1. Primary Hypertension
15.3.2. Secondary Hypertension
15.4. Middle East & Africa Antihypertensive Drugs Market Value Forecast, by Medication Type, 2017–2030
15.4.1. Monotherapy
15.4.2. Combination Therapy
15.4.3. Fixed Dose Combinations
15.4.4. Others
15.5. Middle East & Africa Antihypertensive Drugs Market Value Forecast, by Distribution Channel, 2017–2030
15.5.1. Retail Pharmacies
15.5.2. Hospital Pharmacies
15.5.3. Online Pharmacies
15.5.4. Others
15.6. Middle East & Africa Antihypertensive Drugs Market Value Forecast, by Country/Sub-region, 2017–2030
15.6.1. GCC Countries
15.6.2. South Africa
15.6.3. Israel
15.6.4. Rest of Middle East & Africa
15.7. Middle East & Africa Antihypertensive Drugs Market Attractiveness Analysis
15.7.1. By Drug
15.7.2. By Condition
15.7.3. By Medication Type
15.7.4. By Distribution Channel
15.7.5. By Country/Sub-region
16. Competition Landscape
16.1. Global Antihypertensive Drugs Market Share Analysis, by Company (2018)
16.2. Company Profiles
16.2.1. Pfizer Inc.
16.2.1.1. Company Description
16.2.1.2. Business Overview
16.2.1.3. Financial Overview
16.2.1.4. Strategic Overview
16.2.1.5. SWOT Analysis
16.2.2. Sanofi S.A
16.2.2.1. Company Description
16.2.2.2. Business Overview
16.2.2.3. Financial Overview
16.2.2.4. Strategic Overview
16.2.2.5. SWOT Analysis
16.2.3. Novartis AG
16.2.3.1. Company Description
16.2.3.2. Business Overview
16.2.3.3. Financial Overview
16.2.3.4. Strategic Overview
16.2.3.5. SWOT Analysis
16.2.4. Boehringer Ingelheim GmbH
16.2.4.1. Company Description
16.2.4.2. Business Overview
16.2.4.3. Financial Overview
16.2.4.4. Strategic Overview
16.2.4.5. SWOT Analysis
16.2.5. Actelion Ltd. (Johnson & Johnson Services, Inc.)
16.2.5.1. Company Description
16.2.5.2. Business Overview
16.2.5.3. Financial Overview
16.2.5.4. Strategic Overview
16.2.5.5. SWOT Analysis
16.2.6. F. Hoffmann-La Roche Ltd.
16.2.6.1. Company Description
16.2.6.2. Business Overview
16.2.6.3. Financial Overview
16.2.6.4. Strategic Overview
16.2.6.5. SWOT Analysis
16.2.7. Bayer AG
16.2.7.1. Company Description
16.2.7.2. Business Overview
16.2.7.3. Financial Overview
16.2.7.4. Strategic Overview
16.2.7.5. SWOT Analysis
16.2.8. Daiichi Sankyo Company, Limited
16.2.8.1. Company Description
16.2.8.2. Business Overview
16.2.8.3. Financial Overview
16.2.8.4. Strategic Overview
16.2.8.5. SWOT Analysis
16.2.9. Takeda Pharmaceutical Company Limited
16.2.9.1. Company Description
16.2.9.2. Business Overview
16.2.9.3. Financial Overview
16.2.9.4. Strategic Overview
16.2.9.5. SWOT Analysis