Arthritis Therapeutics Market: Numerous Product and Novel Drug Launches Leading to New Heights
The arthritis therapeutics market, characterized by healthy growth, is witnessing numerous promising pipeline projects and new product launches in parallel to increasing awareness campaigns run by public and private organizations. The patent expiration of blockbuster drugs is putting more pressure on manufacturers to develop effective versions of these drugs, which is projected to pave the way for the advancements of biosimilar products.
According to the Centers for Disease Control and Prevention (CDC) data published in 2018, ~54 Mn adults in the U.S. have been diagnosed with arthritis, and the number will grow to ~78 Mn by 2040. In this fast-paced era, individuals can’t afford to reduce their range of motion, which pertinently entails that those residing in developed countries are massively partaking in the diagnosis and treatment of arthritis as compared to those in developing countries. In the future, as the success of health awareness campaigns increases in developing countries, manufacturers in the arthritis therapeutics market will scramble towards these countries to leverage the first mover’s advantage.
Perpetual Increase in Drug Prices to Impact Health of Arthritis Therapeutics Market
Despite the stronghold of disease-modifying antirheumatic drugs (DMARDs) in the arthritis therapeutics market, next gen antibody therapeutics are found to gain ground in recent times, on account of their higher efficiency. However, the efficiency of these drugs comes at a price, indeed a high one, ranging from US$ 1,000 to US$ 3,000 per month, which could hold back the sales potential of these drugs.
The price of Humira - a default drug for the treatment of arthritis - saw a steep increase in its price by 68.7% over the last five years, which equals to US$ 3,700 for a month-long supply. Also, the wholesale cost of the drug Enbrel has risen by 80.3% in the same time period, as found by Alliance of Community Health Plans. What’s more of an adoption concern for patients is the lack of discounts and deals, and the retail price further rises when they are distributed to retailers and pharmacies. Given the recommendation for a long-term course of arthritis treatment, high cost can affect the monthly budgets of patients, which could negatively impact sales in the arthritis therapeutics market space.
Parenteral Route to Grow as Preferable Drug-consumption Mode
As per the report, in 2019, the parenteral route of drug administration is projected to be used for ~83% cases for arthritis treatment, while in the remaining ~17% cases, the oral and topical route will be preferred. To put this data into perspective, parenteral administration possesses better control over the dose and frequency, thereby ensuring an improved treatment outcome as compared to oral therapeutics. These routes of drug administration, in turn, are also found to offer better bioavailability and metabolism avoidance. On the contrary, patients are liable to maintain a course of oral drugs on their own, and in cases where they miss out on popping a pill, recovery can take a longer time.
Analysts’ Opinion on Arthritis Therapeutics Market
Analysts of the report opine that, the arthritis therapeutics market will record 8.5% more sales in 2019 over 2018, and continue to advance at a CAGR of ~6% during 2019-2027. The high prevalence of arthritis that primarily weakens the joints and degrades the quality of life of patients, is projected to encourage more patients to avail proper treatment options. Given the growing demand, head-to-head trails to boost the efficacy profiles of drugs intensify the competition in the arthritis therapeutics market, and strategic partnership to target new markets backed by innovative product-level approaches will form a profitable deal for manufacturers.
It is worth noting that, retail pharmacies will take over ~78% sales of these therapeutics in the year 2019, which implies the need for market players to strengthen distribution partnerships with retailers of all scales.
Global Arthritis Therapeutics Market: Overview
The global arthritis therapeutics market was valued at ~US$ 43 Bn in 2018, and is projected to expand at a CAGR of ~6% from 2019 to 2027, to reach ~US$ 72.6 Bn by 2027.
Increasing incidence of arthritis, including rheumatoid arthritis, osteoarthritis, psoriatic arthritis, gout, and other types of arthritis across the globe, is a major factor that is likely to fuel the global arthritis therapeutics market.
Ongoing arthritis clinical trials, increase in the geriatric population, rising investments in research & development, increasing demand for biologics, launching of novel products, and surge in mergers and strategic alliances are also anticipated to propel the growth of the global market.
Arthritis is an inflammatory joint condition, which causes pain and stiffness, and worsens with age. More than 100 types of arthritis exists, along with different causes and underlying infections. The common types of arthritis are rheumatoid arthritis, psoriatic arthritis, and osteoarthritis.
Several therapeutics and medications have been developed in recent years to relieve and treat the symptoms of arthritis. The most commonly used drugs belong to the drug class of TNF inhibitors, interleukin inhibitors, non-steroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and other drugs. TNF inhibitors are widely utilized for the treatment of arthritis disorders. Arthritis is a highly underdiagnosed and undertreated medical condition, with a large number of patients unsatisfied with the current treatment options available. This offers significant opportunity to biopharmaceutical players operating in the arthritis therapeutics market to offer novel drugs. The under-penetration of biologic drugs in a majority of developed and emerging markets for the treatment of arthritis offers significant opportunities to global biopharmaceutical players.
A large number of both, small molecules and biologic products are under different phases of clinical trials. Leading companies have made significant investments in clinical R&D, and have established strategic partnerships and collaborations to accelerate new product development.
Global Arthritis Therapeutics Market: Key Segment
Based on type, the global arthritis therapeutics market has been categorized into rheumatoid arthritis, osteoarthritis, psoriatic arthritis, gout, and others. Among these, the rheumatoid arthritis segment is the largest, and is expected to dominate the market during the forecast period. The high market share of the rheumatoid arthritis segment can be attributed to the availability of effective biologics for its treatment. The psoriatic arthritis segment is projected to grow at the highest pace during the forecast period, due to increasing number of psoriasis patients likely to develop psoriatic arthritis.
In terms of drug class, the global arthritis therapeutics market has been divided into TNF inhibitors, interleukin inhibitors, NSAIDs, corticosteroids, xanthine oxidase inhibitors, and others. The TNF inhibitors segment dominates the global market, owing to its higher efficacy rate as compared to other small molecules. Moreover, increasing investments toward the development of TNF inhibitor biologics are likely to drive the segment. The interleukin inhibitors segment is expected to expand at the highest CAGR, owing to ongoing clinical studies supporting their effectiveness, and quick adoption of interleukin inhibitors in gout, PsA, and RA indications.
On the basis of route of administration, the global arthritis therapeutics market has been segmented into oral, parenteral, and topical. The parenteral segment accounted for the largest share of the global market, and is expected to continue its dominance, owing to large volume prescriptions of biologic drugs administered through intravenous and subcutaneous injections.
Based on distribution channel, the global market has been segregated into hospital pharmacies, retail pharmacies, and online pharmacies. The retail pharmacies segment holds a major market share, owing to the easy availability of biologics drugs in retail pharmacies, and increasing retail pharmacy stores across the globe.
Global Arthritis Therapeutics Market: Major Players
Key players operating in the global arthritis therapeutics market include
These players are focused on mergers & acquisitions, development of novel products, launch of biosimilars, and implementation of inorganic and inorganic growth strategies to strengthen their product portfolios and global footprint.
Moreover, companies are attracting investments for the research & development of arthritis drugs in order to improve patient care and remain competitive in the global market.
Key Questions Answered in the Arthritis Therapeutics Market Report
Global Arthritis Therapeutics Market – Segmentation
Type
Drug Class
Route of Administration
Distribution Channel
Region
1. Preface
1.1. Market Definition and Scope
1.2. Market Segmentation
1.3. Key Research Objectives
1.4. Research Highlights
2. Assumptions and Research Methodology
3. Executive Summary: Global Arthritis Therapeutics Market
4. Market Overview
4.1. Introduction
4.1.1. Market Definition
4.1.2. Industry Evolution / Developments
4.2. Overview
4.3. Market Dynamics
4.3.1. Drivers
4.3.2. Restraints
4.3.3. Opportunities
4.4. Global Arthritis Therapeutics Market Analysis and Forecast, 2017–2027
4.4.1. Market Revenue Projections (US$ Mn)
5. Key Insights
5.1. Key product/brand Analysis
5.2. Pipeline Analysis
5.3. Disease Prevalence & Incidence Rate globally with key countries
5.4. Regulatory Scenario by Region/globally
6. Global Arthritis Therapeutics Market Analysis and Forecast, By Type
6.1. Introduction & Definition
6.2. Key Findings / Developments
6.3. Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Type, 2017–2027
6.3.1. Rheumatoid Arthritis
6.3.2. Osteoarthritis
6.3.3. Psoriatic Arthritis
6.3.4. Gout
6.3.5. Others
6.4. Market Attractiveness By Type
7. Global Arthritis Therapeutics Market Analysis and Forecast, By Drug Class
7.1. Introduction & Definition
7.2. Key Findings / Developments
7.3. Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Drug Class, 2017–2027
7.3.1. TNF Inhibitors
7.3.2. Interleukin Inhibitors
7.3.3. NSAIDs
7.3.4. Corticosteroids
7.3.5. Xanthine Oxidase Inhibitors
7.3.6. Others
7.4. Market Attractiveness By Drug Class
8. Global Arthritis Therapeutics Market Analysis and Forecast, By Route of Administration
8.1. Introduction & Definition
8.2. Key Findings / Developments
8.3. Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Route of Administration, 2017–2027
8.3.1. Oral
8.3.2. Parenteral
8.3.3. Topical
8.4. Market Attractiveness By Route of Administration
9. Global Arthritis Therapeutics Market Analysis and Forecast, By Distribution Channel
9.1. Introduction & Definition
9.2. Key Findings / Developments
9.3. Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Distribution Channel, 2017–2027
9.3.1. Hospital Pharmacies
9.3.2. Retail Pharmacies
9.3.3. Online Pharmacies
9.4. Market Attractiveness By Distribution Channel
10. Global Arthritis Therapeutics Market Analysis and Forecast, By Region
10.1. Key Findings
10.2. Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Region
10.2.1. North America
10.2.2. Europe
10.2.3. Asia Pacific
10.2.4. Latin America
10.2.5. Middle East & Africa
10.3. Market Attractiveness By Country/Sub-region /Region
11. North America Arthritis Therapeutics Market Analysis and Forecast
11.1. Introduction
11.1.1. Key Findings
11.2. North America Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Type, 2017–2027
11.2.1. Rheumatoid Arthritis
11.2.2. Osteoarthritis
11.2.3. Psoriatic Arthritis
11.2.4. Gout
11.2.5. Others
11.3. North America Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Drug Class, 2017–2027
11.3.1. TNF Inhibitors
11.3.2. Interleukin Inhibitors
11.3.3. NSAIDs
11.3.4. Corticosteroids
11.3.5. Xanthine Oxidase Inhibitors
11.3.6. Others
11.4. North America Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Route of Administration, 2017–2027
11.4.1. Oral
11.4.2. Parenteral
11.4.3. Topical
11.5. North America Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Distribution Channel, 2017–2027
11.5.1. Hospital Pharmacies
11.5.2. Retail Pharmacies
11.5.3. Online Pharmacies
11.6. North America Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Country/Sub-region, 2017–2027
11.6.1. U.S.
11.6.2. Canada
11.7. North America Market Attractiveness Analysis
11.7.1. By Type
11.7.2. By Drug Class
11.7.3. By Route of Administration
11.7.4. By Distribution Channel
11.7.5. By Country/Sub-region
12. Europe Arthritis Therapeutics Market Analysis and Forecast
12.1. Introduction
12.1.1. Key Findings
12.2. Europe Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Type, 2017–2027
12.2.1. Rheumatoid Arthritis
12.2.2. Osteoarthritis
12.2.3. Psoriatic Arthritis
12.2.4. Gout
12.2.5. Others
12.3. Europe Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Drug Class, 2017–2027
12.3.1. TNF Inhibitors
12.3.2. Interleukin Inhibitors
12.3.3. NSAIDs
12.3.4. Corticosteroids
12.3.5. Xanthine Oxidase Inhibitors
12.3.6. Others
12.4. Europe Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Route of Administration, 2017–2027
12.4.1. Oral
12.4.2. Parenteral
12.4.3. Topical
12.5. Europe Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Distribution Channel, 2017–2027
12.5.1. Hospital Pharmacies
12.5.2. Retail Pharmacies
12.5.3. Online Pharmacies
12.6. Europe Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Country/Sub-region, 2017–2027
12.6.1. Germany
12.6.2. U.K.
12.6.3. France
12.6.4. Spain
12.6.5. Italy
12.6.6. Rest of Europe
12.7. Europe Market Attractiveness Analysis
12.7.1. By Type
12.7.2. By Drug Class
12.7.3. By Route of Administration
12.7.4. By Distribution Channel
12.7.5. By Country/Sub-region
13. Asia Pacific Arthritis Therapeutics Market Analysis and Forecast
13.1. Introduction
13.1.1. Key Findings
13.2. Asia Pacific Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Type, 2017–2027
13.2.1. Rheumatoid Arthritis
13.2.2. Osteoarthritis
13.2.3. Psoriatic Arthritis
13.2.4. Gout
13.2.5. Others
13.3. Asia Pacific Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Drug Class, 2017–2027
13.3.1. TNF Inhibitors
13.3.2. Interleukin Inhibitors
13.3.3. NSAIDs
13.3.4. Corticosteroids
13.3.5. Xanthine Oxidase Inhibitors
13.3.6. Others
13.4. Asia Pacific Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Route of Administration, 2017–2027
13.4.1. Oral
13.4.2. Parenteral
13.4.3. Topical
13.5. Asia Pacific Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Distribution Channel, 2017–2027
13.5.1. Hospital Pharmacies
13.5.2. Retail Pharmacies
13.5.3. Online Pharmacies
13.6. Asia Pacific Arthritis Therapeutics Market Value (US$ Mn) Forecast, By Country/Sub-region /Sub-region, 2017–2027
13.6.1. China
13.6.2. Japan
13.6.3. India
13.6.4. Australia & New Zealand
13.6.5. Rest of Asia Pacific
13.7. Asia Pacific Market Attractiveness Analysis
13.7.1. By Type
13.7.2. By Drug Class
13.7.3. By Route of Administration
13.7.4. By Distribution Channel
13.7.5. By Country/Sub-region
14. Latin America Arthritis Therapeutics Market Analysis and Forecast
14.1. Introduction
14.1.1. Key Findings
14.2. Latin America Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Type, 2017–2027
14.2.1. Rheumatoid Arthritis
14.2.2. Osteoarthritis
14.2.3. Psoriatic Arthritis
14.2.4. Gout
14.2.5. Others
14.3. Latin America Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Drug Class, 2017–2027
14.3.1. TNF Inhibitors
14.3.2. Interleukin Inhibitors
14.3.3. NSAIDs
14.3.4. Corticosteroids
14.3.5. Xanthine Oxidase Inhibitors
14.3.6. Others
14.4. Latin America Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Route of Administration, 2017–2027
14.4.1. Oral
14.4.2. Parenteral
14.4.3. Topical
14.5. Latin America Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Distribution Channel, 2017–2027
14.5.1. Hospital Pharmacies
14.5.2. Retail Pharmacies
14.5.3. Online Pharmacies
14.6. Latin America Arthritis Therapeutics Market Value (US$ Mn) Forecast, By Country/Sub-region /Sub-region, 2017–2027
14.6.1. Brazil
14.6.2. Mexico
14.6.3. Rest of Latin America
14.7. Latin America Market Attractiveness Analysis
14.7.1. By Type
14.7.2. By Drug Class
14.7.3. By Route of Administration
14.7.4. By Distribution Channel
14.7.5. By Country/Sub-region
15. Middle East & Africa Arthritis Therapeutics Market Analysis and Forecast
15.1. Introduction
15.1.1. Key Findings
15.2. Middle East & Africa Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Type, 2017–2027
15.2.1. Rheumatoid Arthritis
15.2.2. Osteoarthritis
15.2.3. Psoriatic Arthritis
15.2.4. Gout
15.2.5. Others
15.3. Middle East & Africa Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Drug Class, 2017–2027
15.3.1. TNF Inhibitors
15.3.2. Interleukin Inhibitors
15.3.3. NSAIDs
15.3.4. Corticosteroids
15.3.5. Xanthine Oxidase Inhibitors
15.3.6. Others
15.4. Middle East & Africa Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Route of Administration, 2017–2027
15.4.1. Oral
15.4.2. Parenteral
15.4.3. Topical
15.5. Middle East & Africa Arthritis Therapeutics Market Value (US$ Mn) Forecast, by Distribution Channel, 2017–2027
15.5.1. Hospital Pharmacies
15.5.2. Retail Pharmacies
15.5.3. Online Pharmacies
15.6. Middle East & Africa Arthritis Therapeutics Market Value (US$ Mn) Forecast, By Country/Sub-region , 2017–2027
15.6.1. GCC Countries
15.6.2. South Africa
15.6.3. Rest of Middle East & Africa
15.7. Middle East & Africa Market Attractiveness Analysis
15.7.1. By Type
15.7.2. By Drug Class
15.7.3. By Route of Administration
15.7.4. By Distribution Channel
15.7.5. By Country/Sub-region
16. Competition Landscape
16.1. Market Share Analysis By Company (2018)
16.2. Company Profiles
16.2.1. Novartis AG
16.2.1.1. Company Overview (HQ, Business Segments, Employee Strength)
16.2.1.2. Financial Overview
16.2.1.3. Product Portfolio
16.2.1.4. Strategic Overview
16.2.1.5. SWOT Analysis
16.2.2. Eli Lilly and Company
16.2.2.1. Company Overview (HQ, Business Segments, Employee Strength)
16.2.2.2. Financial Overview
16.2.2.3. Product Portfolio
16.2.2.4. Strategic Overview
16.2.2.5. SWOT Analysis
16.2.3. Amgen, Inc.
16.2.3.1. Company Overview (HQ, Business Segments, Employee Strength)
16.2.3.2. Financial Overview
16.2.3.3. Product Portfolio
16.2.3.4. Strategic Overview
16.2.3.5. SWOT Analysis
16.2.4. Merck & Co., Inc.
16.2.4.1. Company Overview (HQ, Business Segments, Employee Strength)
16.2.4.2. Financial Overview
16.2.4.3. Product Portfolio
16.2.4.4. Strategic Overview
16.2.4.5. SWOT Analysis
16.2.5. Bristol-Myers Squibb Company
16.2.5.1. Company Overview (HQ, Business Segments, Employee Strength)
16.2.5.2. Financial Overview
16.2.5.3. Product Portfolio
16.2.5.4. Strategic Overview
16.2.5.5. SWOT Analysis
16.2.6. Pfizer, Inc.
16.2.6.1. Company Overview (HQ, Business Segments, Employee Strength)
16.2.6.2. Financial Overview
16.2.6.3. Product Portfolio
16.2.6.4. Strategic Overview
16.2.6.5. SWOT Analysis
16.2.7. AbbVie, Inc.
16.2.7.1. Company Overview (HQ, Business Segments, Employee Strength)
16.2.7.2. Financial Overview
16.2.7.3. Product Portfolio
16.2.7.4. Strategic Overview
16.2.7.5. SWOT Analysis
16.2.8. Janssen Global Services, LLC (Johnson & Johnson)
16.2.8.1. Company Overview (HQ, Business Segments, Employee Strength)
16.2.8.2. Financial Overview
16.2.8.3. Product Portfolio
16.2.8.4. Strategic Overview
16.2.8.5. SWOT Analysis
16.2.9. F. Hoffmann-La Roche Ltd
16.2.9.1. Company Overview (HQ, Business Segments, Employee Strength)
16.2.9.2. Financial Overview
16.2.9.3. Product Portfolio
16.2.9.4. Strategic Overview
16.2.9.5. SWOT Analysis
16.2.10. Sanofi
16.2.10.1. Company Overview (HQ, Business Segments, Employee Strength)
16.2.10.2. Financial Overview
16.2.10.3. Product Portfolio
16.2.10.4. Strategic Overview
16.2.10.5. SWOT Analysis