Cell Culture Market (Product: Instruments, Media, Sera, and Reagents; and End-user: Biotechnology Companies, Pharmaceutical Companies, Academic Institutes, and Research Institutes) - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2021-2030

Cell Culture Market Outlook 2028

The global cell culture market was valued at US$ 16.6 Bn in 2020

It is estimated to expand at a CAGR of 6.4% from 2021 to 2028

The global cell culture market is expected to reach the value of US$ 30 Bn by the end of 2028

Analysts’ Viewpoint on Cell Culture Market Scenario

The rising prevalence of cancer and cardiovascular diseases is driving the global cell culture market. Biological products produced from the cell culture are used for the treatment of these diseases. Technological advancement in pharmaceutical industry creating potential revenue opportunities for the market players operating in the cell culture market. The increasing investment in R&D in cell culture to explore innovative solutions for the treatment of various illnesses in the body is accelerating market growth. Market players are exploring new approaches to culturing or utilizing cells for various applications. Rapid expansion of pharmaceutical companies, growth and advancement in drug development & discovery, rapidly expanding clinical research institutes in developed regions are fueling the growth of the cell culture market. High costs and unavailability of suitable infrastructure for research activities are the factors affecting the growth of the global cell culture market.

Rise in Demand for Biopharmaceuticals Promotes Market Growth

Due to the increasing demand for biosimilar and biologics products for the treatment of cancer and various other chronic and cardiovascular diseases, cell culture method is found to be effective, efficient in the biopharmaceutical sector. Cell culture products increase productivity by lowering manufacturing costs. Cell culture is a process of removing cells from an animal or plant source, and use these cells for creating biosimilar or biologic therapeutics. These cells can be kept and grow in a controlled environment such as ideal temperature, gases, pH, and humidity. These factors are essential for the growth and proliferation of the cells. Cell removal can be carried out either by mechanical or enzymatic method before cultivation. The cells to be grown can also be derived from a cell line or cell strain that has already been established. Biosimilar products has gained tremendous popularity in North America and Europe. This factor contributes to the global cell culture market growth.

Challenges Associated with Fetal Bovine Serum (FBS) in Cell Culture Market

Market players are targeting the rising production of fetal bovine serum (FBS) by innovative strategies. Fetal bovine serum (FBS) is made from the bovine fetuses that are removed from pregnant cows during slaughter. Animal cell culture mediums contain fetal bovine serum (FBS). It is generally obtained with a cardiac puncture without the need of anesthetic. Increase in awareness of animal welfare activities is the factor affecting the growth of the cell culture market. There is a huge reduction in the fetal bovine serum production across the globe. This factor is likely to affect the market growth in the upcoming years.

Profitable Revenue Opportunities for North America Market Players

North America is expected to account for the major share in the global cell culture market during the forecast period. The lucrative presence of market players operating in the North America cell culture market is the major factor responsible for the market growth in the region. The North America cell culture market is also driven by the strong support from government, increasing investment in cell-based research & development, regulatory approvals for cell culture-based vaccines, rapidly rising prevalence of diseases such as cancer, etc. Market players working in the cell culture market in North America are expected to witness potential growth opportunities in the market. In addition, technological advancement in healthcare, high biopharmaceutical R&D expenditure, and the greater adoption of advanced technologies are also fueling the growth of the market in the region. Countries in the Asia Pacific market such as China and India are the fastest growing region in the cell culture market. Rapid urbanization and increasing investment in research activities are the key factors contributing to the market growth in Asia Pacific.

Impact of COVID-19 and Increase in Product Development

The rapidly spreading coronavirus across the globe has created opportunities for manufacturers operating in the global cell culture market due to rising need of vaccines, which demand research-based activities, along with clinical trial of vaccines. The global cell culture market is booming due to the surging demand for biopharmaceuticals, increase in product development by key market contributors, and development of novel vaccines. There is an increasing demand for cost-effective, reliable, low-risk, and highly efficient cell culture products such as bioreactors, media, reagents, and sera for the creation of high-yield cell lines. In order to fulfill this demand, many cell culture manufacturers are focusing on increasing production of innovative products.

Cell Culture Market: Overview

The global cell culture market for the historical period 2017–2019 and forecast period 2021–2028, rise in demand for biopharmaceuticals, increase in product development by players, and rapid development of novel vaccines are projected to drive the global cell culture market during the forecast period

Increase in Product Development by Manufacturers: Key Driver

Demand for cost-effective and highly efficient cell culture items such as bioreactors, media, reagents, and sera for the creation of high-yield cell lines has increased, resulting in an increase in the number of new product launches. This factor is expected to fuel the growth of the global cell culture market during the forecast period.

Major manufacturers are continuously attempting to diversify their product line by introducing new and innovative systems for cost-effective, low-risk large-scale production. Merck, for instance, introduced capsule filters in 2018 to help reduce the possibility of contamination in bioreactors. Mycoplasma and bacteria are separated from cell culture media using these filters.

Rise in Demand for Biopharmaceuticals to Boost Market Growth

One of the most significant phases in the creation of biosimilar/biologic therapeutics is cell culture, which helps to boost efficiency and productivity while lowering manufacturing costs

Increase in demand for biosimilars and other biologics for the treatment of chronic diseases such as cancer and diabetes globally has resulted in rise in demand for efficient and cost-effective products. This is expected to drive the global cell culture market during the forecast period.

Infliximab, the first biosimilar monoclonal antibody, was approved for autoimmune diseases, which includes Crohn's disease, ulcerative colitis, and rheumatoid arthritis, and quickly gained market share in key countries in Europe. In Europe, there are now three competing infliximab biosimilar brands: MundiPharma's Remsima, Pfizer/Inflectra, Hospira's and Biogen's Flixabi.

With approximately 240 biosimilars in development (counting only those that have been publicly revealed), launches will become more frequent. This is likely to drive the global cell culture market over the next few years.

Ethical Issues Associated with Use of Fetal Bovine Serum to Hamper Market

Animal cell culture mediums frequently contain fetal bovine serum (FBS). It is made from bovine fetuses that are removed from pregnant cows during slaughter. FBS is generally obtained with a cardiac puncture without the need of anesthetic. The current technique of fetal blood collecting is inhumane since fetuses are likely to be in pain and/or discomfort.

Due to increased criticism from animal welfare organizations, production of fetal bovine serum is likely to decline in the next few years. This drop in FBS production is expected to act as a restraint of the global cell culture market during the forecast period.

Apart from moral difficulties, there are a number of scientific and technological issues with the use of FBS in cell culture, which are prompting users to choose for alternatives

Cell Culture Market: Competition Landscape

This report profiles major players in the global cell culture market based on various attributes such as company overview, financial overview, product portfolio, business strategies, and recent developments

The global cell culture market is consolidated with the presence of five major global players

Leading players operating in the global cell culture market are

• Thermo Fisher Scientific, Inc.
• Merck KGaA
• GE Healthcare
• Lonza Group
• Sartorius AG
• Becton
• Dickinson and Company
• Corning, Inc.
• Eppendorf AG
• VWR International
• PromoCell GmbH, among others

Key Questions Answered in Cell Culture Market Report

• What is the scope of growth of product companies in the global cell culture market?
• What will be the Y-o-Y growth of the global cell culture market between 2017 and 2028?
• What is the influence of changing trends on the global cell culture market?
• Will North America be the most profitable market for cell culture providers?
• Which factors are anticipated to hamper the growth of the global cell culture market during the forecast period?
• Which are the leading companies in the global cell culture market?

Cell Culture Market – Segmentation

Product

• Instruments
• Media
• Sera
• Reagents

End-user

• Biotechnology Companies
• Pharmaceutical Companies
• Academic Institutes
• Research Institutes

Region

• North America
• Europe
• Asia Pacific
• Latin America
• Middle East & Africa

1. Preface

    1.1. Market Definition

    1.2. Market Segmentation

    1.3. Key Research Objectives

    1.4. Research Highlights

2. Assumptions and Research Methodology

3. Executive Summary: Global Cell Culture Market

4. Market Overview

    4.1. Introduction

        4.1.1. Segment Definition

    4.2. Overview

    4.3. Market Dynamics

        4.3.1. Drivers

        4.3.2. Restraints Snapshot

        4.3.3. Opportunities

    4.4. Global Cell Culture Market Analysis and Forecast, 2017-2028

        4.4.1. Market Revenue Projections (US$ Mn)

5. Key Insights

    5.1. Cell Culture Market: Overview

    5.2. Pricing Analysis

    5.3. Key Industry Events (mergers, acquisitions, partnerships, collaborations, etc.)

    5.4. COVID-19 Pandemic Impact on Industry (value chain and short / mid / long term impact)

6. Global Cell Culture Market Analysis, by Product

    6.1. Introduction

    6.2. Key Insights

    6.3. Global Cell Culture Market Analysis, by Product

        6.3.1. Instruments

            6.3.1.1. Cell Culture Vessels (Bioreactor)

            6.3.1.2. Carbon dioxide Incubators

            6.3.1.3. Biosafety Cabinets

            6.3.1.4. Cryogenic Tanks

            6.3.1.5. Others

        6.3.2. Media

            6.3.2.1. Chemically Defined

            6.3.2.2. Classical Media

            6.3.2.3. Lysogeny Broth

            6.3.2.4. Serum-free Media

            6.3.2.5. Protein-free Media

            6.3.2.6. Specialty Media

        6.3.3. Sera

            6.3.3.1. Fetal Bovine Serum (FBS)

            6.3.3.2. Others

        6.3.4. Reagents

            6.3.4.1. Growth Factors & Cytokines

            6.3.4.2. Albumin

            6.3.4.3. Protease Inhibitor

            6.3.4.4. Thrombin

            6.3.4.5. Attachment Factors

            6.3.4.6. Amino Acids

            6.3.4.7. Others

    6.4. Global Cell Culture Market Forecast, by Product

        6.4.1. Instruments

        6.4.2. Media

        6.4.3. Sera

        6.4.4. Reagents

    6.5. Global Cell Culture Market Attractiveness Analysis, by Product

        6.5.1. Instruments

        6.5.2. Media

        6.5.3. Sera

        6.5.4. Reagents

7. Global Cell Culture Market Analysis, by End-user

    7.1. Introduction

    7.2. Key Insights

    7.3. Global Cell Culture Market Analysis, by End-user

        7.3.1. Biotechnology Industry

        7.3.2. Pharmaceutical Industry

        7.3.3. Academic Institutes

        7.3.4. Research Institutes

    7.4. Global Cell Culture Market Forecast, by End-user

        7.4.1. Biotechnology Industry

        7.4.2. Pharmaceutical Industry

        7.4.3. Academic Institutes

        7.4.4. Research Institutes

    7.5. Global Cell Culture Market Attractiveness Analysis, by End-user

        7.5.1. Biotechnology Industry

        7.5.2. Pharmaceutical Industry

        7.5.3. Academic Institutes

        7.5.4. Research Institutes

8. Global Cell Culture Market Analysis, by Region

    8.1. Global Cell Culture Market Forecast, by Region, 2015–2025

        8.1.1. North America

        8.1.2. Europe

        8.1.3. Asia Pacific

        8.1.4. Latin America

        8.1.5. Middle East & Africa

    8.2. Global Cell Culture Market Value Share Analysis, by Region

    8.3. Global Cell Culture Market Attractiveness Analysis, by Region

9. North America Cell Culture Market Analysis

    9.1. North America Cell Culture Market Key Findings

    9.2. North America Cell Culture Market Overview

    9.3. North America Cell Culture Market Value Share Analysis, by Product

        9.3.1. Instruments

            9.3.1.1. Cell Culture Vessels (Bioreactor)

            9.3.1.2. Carbon dioxide Incubators

            9.3.1.3. Biosafety Cabinets

            9.3.1.4. Cryogenic Tanks

            9.3.1.5. Others

        9.3.2. Media

            9.3.2.1. Chemically Defined

            9.3.2.2. Classical Media

            9.3.2.3. Lysogeny Broth

            9.3.2.4. Serum-free Media

            9.3.2.5. Protein-free Media

            9.3.2.6. Specialty Media

        9.3.3. Sera

            9.3.3.1. Fetal Bovine Serum (FBS)

            9.3.3.2. Others

        9.3.4. Reagents

            9.3.4.1. Growth Factors & Cytokines

            9.3.4.2. Albumin

            9.3.4.3. Protease Inhibitor

            9.3.4.4. Thrombin

            9.3.4.5. Attachment Factors

            9.3.4.6. Amino Acids

            9.3.4.7. Others

    9.4. North America Cell Culture Market Value Share Analysis, by End-user

        9.4.1. Biotechnology Industry

        9.4.2. Pharmaceutical Industry

        9.4.3. Academic Institutes

        9.4.4. Research Institutes

    9.5. North America Cell Culture Market Forecast, by Country

        9.5.1. U.S.

        9.5.2. Canada

    9.6. North America Cell Culture Market Attractiveness Analysis

        9.6.1. Product

        9.6.2. End-user

        9.6.3. Country

10. Europe Cell Culture Market Analysis

    10.1. Europe Cell Culture Market Key Findings

    10.2. Europe Cell Culture Market Overview

    10.3. Europe Cell Culture Market Value Share Analysis, by Product

        10.3.1. Instruments

            10.3.1.1. Cell Culture Vessels (Bioreactor)

            10.3.1.2. Carbon dioxide Incubators

            10.3.1.3. Biosafety Cabinets

            10.3.1.4. Cryogenic Tanks

            10.3.1.5. Others

        10.3.2. Media

            10.3.2.1. Chemically Defined

            10.3.2.2. Classical Media

            10.3.2.3. Lysogeny Broth

            10.3.2.4. Serum-free Media

            10.3.2.5. Protein-free Media

            10.3.2.6. Specialty Media

        10.3.3. Sera

            10.3.3.1. Fetal Bovine Serum (FBS)

            10.3.3.2. Others

        10.3.4. Reagents

            10.3.4.1. Growth Factors & Cytokines

            10.3.4.2. Albumin

            10.3.4.3. Protease Inhibitor

            10.3.4.4. Thrombin

            10.3.4.5. Attachment Factors

            10.3.4.6. Amino Acids

            10.3.4.7. Others

    10.4. Europe Cell Culture Market Value Share Analysis, by End-user

        10.4.1. Biotechnology Industry

        10.4.2. Pharmaceutical Industry

        10.4.3. Academic Institutes

        10.4.4. Research Institutes

    10.5. Europe Cell Culture Market Forecast, by Country/Sub-region

        10.5.1. Germany

        10.5.2. U.K.

        10.5.3. France

        10.5.4. Italy

        10.5.5. Spain

        10.5.6. Rest of Europe

    10.6. Europe Cell Culture Market Attractiveness Analysis

        10.6.1. Product

        10.6.2. End-user

        10.6.3. Country/Sub-region

11. Asia Pacific Cell Culture Market Analysis

    11.1. Asia Pacific Cell Culture Market Key Findings

    11.2. Asia Pacific Cell Culture Market Overview

    11.3. Asia Pacific Cell Culture Market Value Share Analysis, by Product

        11.3.1. Instruments

            11.3.1.1. Cell Culture Vessels (Bioreactor)

            11.3.1.2. Carbon dioxide Incubators

            11.3.1.3. Biosafety Cabinets

            11.3.1.4. Cryogenic Tanks

            11.3.1.5. Others

        11.3.2. Media

            11.3.2.1. Chemically Defined

            11.3.2.2. Classical Media

            11.3.2.3. Lysogeny Broth

            11.3.2.4. Serum-free Media

            11.3.2.5. Protein-free Media

            11.3.2.6. Specialty Media

        11.3.3. Sera

            11.3.3.1. Fetal Bovine Serum (FBS)

            11.3.3.2. Others

        11.3.4. Reagents

            11.3.4.1. Growth Factors & Cytokines

            11.3.4.2. Albumin

            11.3.4.3. Protease Inhibitor

            11.3.4.4. Thrombin

            11.3.4.5. Attachment Factors

            11.3.4.6. Amino Acids

            11.3.4.7. Others

    11.4. Asia Pacific Cell Culture Market Value Share Analysis, by End-user

        11.4.1. Biotechnology Industry

        11.4.2. Pharmaceutical Industry

        11.4.3. Academic Institutes

        11.4.4. Research Institutes

    11.5. Asia Pacific Cell Culture Market Forecast, by Country/Sub-region

        11.5.1. China

        11.5.2. India

        11.5.3. Japan

        11.5.4. Australia & New Zealand

        11.5.5. Rest of Asia Pacific

    11.6. Asia Pacific Cell Culture Market Attractiveness Analysis

        11.6.1. Product

        11.6.2. End-user

        11.6.3. Country/Sub-region

12. Latin America Cell Culture Market Analysis

    12.1. Latin America Cell Culture Market Key Findings

    12.2. Latin America Cell Culture Market Overview

    12.3. Latin America Cell Culture Market Value Share Analysis, by Product

        12.3.1. Instruments

            12.3.1.1. Cell Culture Vessels (Bioreactor)

            12.3.1.2. Carbon dioxide Incubators

            12.3.1.3. Biosafety Cabinets

            12.3.1.4. Cryogenic Tanks

            12.3.1.5. Others

        12.3.2. Media

            12.3.2.1. Chemically Defined

            12.3.2.2. Classical Media

            12.3.2.3. Lysogeny Broth

            12.3.2.4. Serum-free Media

            12.3.2.5. Protein-free Media

            12.3.2.6. Specialty Media

        12.3.3. Sera

            12.3.3.1. Fetal Bovine Serum (FBS)

            12.3.3.2. Others

        12.3.4. Reagents

            12.3.4.1. Growth Factors & Cytokines

            12.3.4.2. Albumin

            12.3.4.3. Protease Inhibitor

            12.3.4.4. Thrombin

            12.3.4.5. Attachment Factors

            12.3.4.6. Amino Acids

            12.3.4.7. Others

    12.4. Latin America Cell Culture Market Value Share Analysis, by End-user

        12.4.1. Biotechnology Industry

        12.4.2. Pharmaceutical Industry

        12.4.3. Academic Institutes

        12.4.4. Research Institutes

    12.5. Latin America Cell Culture Market Forecast, by Country/Sub-region

        12.5.1. Brazil

        12.5.2. Mexico

        12.5.3. Rest of Latin America

    12.6. Latin America Cell Culture Market Attractiveness Analysis

        12.6.1. Product

        12.6.2. End-user

        12.6.3. Country/Sub-region

13. Middle East & Africa Cell Culture Market Analysis

    13.1. Middle East & Africa Cell Culture Market Key Findings

    13.2. Middle East & Africa Cell Culture Market Overview

    13.3. Middle East & Africa Cell Culture Market Value Share Analysis, by Product

        13.3.1. Instruments

            13.3.1.1. Cell Culture Vessels (Bioreactor)

            13.3.1.2. Carbon dioxide Incubators

            13.3.1.3. Biosafety Cabinets

            13.3.1.4. Cryogenic Tanks

            13.3.1.5. Others

        13.3.2. Media

            13.3.2.1. Chemically Defined

            13.3.2.2. Classical Media

            13.3.2.3. Lysogeny Broth

            13.3.2.4. Serum-free Media

            13.3.2.5. Protein-free Media

            13.3.2.6. Specialty Media

        13.3.3. Sera

            13.3.3.1. Fetal Bovine Serum (FBS)

            13.3.3.2. Others

        13.3.4. Reagents

            13.3.4.1. Growth Factors & Cytokines

            13.3.4.2. Albumin

            13.3.4.3. Protease Inhibitor

            13.3.4.4. Thrombin

            13.3.4.5. Attachment Factors

            13.3.4.6. Amino Acids

            13.3.4.7. Others

    13.4. Middle East & Africa Cell Culture Market Value Share Analysis, by End-user

        13.4.1. Biotechnology Industry

        13.4.2. Pharmaceutical Industry

        13.4.3. Academic Institutes

        13.4.4. Research Institutes

    13.5. Middle East & Africa Cell Culture Market Forecast, by Country/Sub-region

        13.5.1. GCC Countries

        13.5.2. South Africa

        13.5.3. Rest of Middle East & Africa

    13.6. Middle East & Africa Cell Culture Market Attractiveness Analysis

        13.6.1. Product

        13.6.2. End-user

        13.6.3. Country/Sub-region

14. Competition Landscape

    14.1. Global Cell Culture Market Share Analysis, by Company, 2016

    14.2. Company Profiles

        14.2.1. Sartorius AG

            14.2.1.1. Overview (HQ, Employee Strength, Business Segments)

            14.2.1.2. Financials

            14.2.1.3. Recent Developments

            14.2.1.4. Strategy

        14.2.2. Thermo Fisher Scientific, Inc.

            14.2.2.1. Overview (HQ, Employee Strength, Business Segments)

            14.2.2.2. Financials

            14.2.2.3. Recent Developments

            14.2.2.4. Strategy

        14.2.3. Eppendorf AG

            14.2.3.1. Overview (HQ, Employee Strength, Business Segments)

            14.2.3.2. Financials

            14.2.3.3. Recent Developments

            14.2.3.4. Strategy

        14.2.4. GE Healthcare

            14.2.4.1. Overview (HQ, Employee Strength, Business Segments)

            14.2.4.2. Financials

            14.2.4.3. Recent Developments

            14.2.4.4. Strategy

        14.2.5. Corning Incorporated

            14.2.5.1. Overview (HQ, Employee Strength, Business Segments)

            14.2.5.2. Financials

            14.2.5.3. Recent Developments

            14.2.5.4. Strategy

        14.2.6. Becton, Dickinson and Company

            14.2.6.1. Overview (HQ, Employee Strength, Business Segments)

            14.2.6.2. Financials

            14.2.6.3. Recent Developments

            14.2.6.4. Strategy

        14.2.7. Merck KGaA

            14.2.7.1. Overview (HQ, Employee Strength, Business Segments)

            14.2.7.2. Financials

            14.2.7.3. Recent Developments

            14.2.7.4. Strategy

        14.2.8. Lonza

            14.2.8.1. Overview (HQ, Employee Strength, Business Segments)

            14.2.8.2. Financials

            14.2.8.3. Recent Developments

            14.2.8.4. Strategy

        14.2.9. VWR International, LLC

            14.2.9.1. Overview (HQ, Employee Strength, Business Segments)

            14.2.9.2. Financials

            14.2.9.3. Recent Developments

            14.2.9.4. Strategy

        14.2.10. PromoCell GmbH

            14.2.10.1. Overview (HQ, Employee Strength, Business Segments)

            14.2.10.2. Financials

            14.2.10.3. Recent Developments

            14.2.10.4. Strategy