Oligonucleotide Synthesis Market (Product - Reagents & Consumables, Equipment, and Synthesized Oligonucleotides (DNA Oligonucleotides and RNA Oligonucleotides); Application - Research (Polymerase Chain Reaction and Next Generation Sequencing), Therapeutics (Antisense Oligonucleotides, and Nucleic Acid Aptamers), and Diagnostics; End User - Biotechnology & Pharmaceutical Companies, Research Institutes, and Diagnostic Laboratories) - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2019 - 2030

Description

The global oligonucleotide synthesis market for the historical period 2017–2018 and forecast period 2019–2027, Increasing use of synthesized oligonucleotides in diagnostics and research applications, and Technological advancements in synthetic chemistry are projected to drive the global oligonucleotide synthesis market during the forecast period

According to the report, the global oligonucleotide synthesis market was valued at US$ 1,966.2 Mn in 2018 and is anticipated to expand at a CAGR of 9.5% from 2019 to 2030

Technological advancements in synthetic chemistry to Drive Global Oligonucleotide Synthesis: Key Drivers

The advances in the technological development of organic molecules are expected to drive the growth of the oligonucleotide synthesis market

The advanced synthesis of oligonucleotides provides longer oligos with better sequence fidelity and higher purity that can be used in a number of molecular biology applications

Various pharmaceutical and biotechnology companies are continuously  working on developing newer and advanced methods in synthetic chemistry

For instance, Integrated DNA Technologies, leader of synthesized oligonucleotides has developed various pioneered methods to synthesize oligonucleotides of extreme lengths. The company has developed oligonucleotides up to 200 base length which is used with mass spectrometry for the manufacture of mini-genes.

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Increasing use of Synthesized Oligonucleotides in Diagnostics and Research Applications Boost Market Growth

Oligonucleotides have a wide range of applications in areas such as molecular biology, biotechnology, and diagnosis

Natural oligonucleotides have been extensively used for the selection and determination of DNA sequences (hybridization probes or affinity purification), gene construction, and site-directed mutagenesis

They constitute the basic reagents for PCR technologies. They are also used to selectively inhibit gene expression in in vitro studies for diagnostic purpose and more recently, their ability to interact with proteins has generated immense opportunity for therapeutic use.

Along with diagnostics, they are widely used in research studies. Combinatorial technology is another research area where oligonucleotides and their analogs are extensively employed.

Limitations in the Synthesis of Oligonucleotides to Hamper Market

An oligonucleotide is a single-stranded chain consisting of a number of nucleoside units linked together by phosphodiester bridges

Mostly in oligonucleotide synthesis, phosphodiesters are formed between a 3’-hydroxyl group bearing a phosphate derivative and a 5’-hydroxyl group of another nucleoside

The occurrence of side reactions sets practical limits for the length of synthetic DNA oligonucleotides (up to about 200 nucleotide residues) because the number of errors accumulates with the length of the oligonucleotide being synthesized

To synthesize RNA with longer nucleotides base, that is more than 50 nucleotides is very complex and difficult to prepare

But, most biologically important RNA molecules such as ribozymes, aptamers, and riboswitches are significantly longer than 50 nucleotides, so new approaches for the synthesis of RNA analogs are urgently required

Global Oligonucleotide Synthesis Market: Competitive Landscape

This report profiles major players in the global oligonucleotide synthesis market based on various attributes such as company overview, financial overview, product portfolio, business strategies, and recent developments

The global oligonucleotide synthesis market is highly fragmented, with the presence of a number of international as well as regional players

Leading players operating in the global Oligonucleotide Synthesis market are

  • GE Healthcare
  • Thermo Fischer Scientific
  • Agilent Technologies, Inc.
  • Merck KGaA
  • Integrated DNA Technologies, Inc.
  • Kaneka Eurogentec S.A
  • BioAutomation
  • Gene Design, Inc.
  • Eurofins Genomics
  • ATDBio, Ltd..

Global Oligonucleotide Synthesis Market: Key Developments

Key players in the global oligonucleotide synthesis market are engaged in regulatory approvals, technologically advanced products, launch of new products, and acquisition & collaborative agreements with other companies. These strategies are likely to fuel the growth of the global oligonucleotide synthesis market. A few expansion strategies adopted by players operating in the global oligonucleotide Synthesis market are:

In May 2017, GE Healthcare announced the launch of its Superdex 30 Increase, a new generation column resin for small-scale preparative purification and analysis, adding another product to the already existing wide portfolio of Superdex Increase family of SEC columns.

The report on the global oligonucleotide synthesis market discussed individual strategies, followed by company profiles of manufacturers of oligonucleotide synthesis. The competitive landscape section has been included in the report to provide readers with a dashboard view and a company market share analysis of key players operating in the global oligonucleotide synthesis market.

Key Questions Answered in Global Oligonucleotide Synthesis Market Report

  • What is the scope of growth of product companies in the global oligonucleotide synthesis market?
  • What will be the Y-o-Y growth of the global oligonucleotide synthesis market between 2019 and 2027?
  • What is the influence of changing trends in technologies on the global oligonucleotide synthesis market?
  • Will North America continue to be the most profitable market for oligonucleotide synthesis providers?
  • Which factors are anticipated to hamper the growth of the global oligonucleotide synthesis market during the forecast period?
  • Which are the leading companies in the global oligonucleotide synthesis market?

Global Oligonucleotide Synthesis Market – Segmentation

Product Product Type

  • Reagents & Consumables
  • Equipment
  • Synthesized Oligonucleotides
  • DNA
  • RNA
  • Others

Applications

  • Research
  • Polymerase Chain Reaction
  • Next Generation Sequencing
  • Others
  • Therapeutics
  • Antisense Oligonucleotides
  • Nucleic Acid Aptamers
  • Diagnostic

End User

  • Biotech & Pharma Companies
  • Research Inst.
  • Diagnostic Labs

Region

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • MEA

TABLE OF CONTENT

1. Preface

    1.1. Market Definition and Scope

    1.2. Market Segmentation

    1.3. Key Research Objectives

    1.4. Research Highlights

2. Assumptions and Research Methodology

3. Executive Summary: Global Oligonucleotide Synthesis Market

4. Market Overview

    4.1. Introduction

        4.1.1. Product Type Definition

        4.1.2. Industry Evolution / Developments

    4.2. Overview

    4.3. Market Dynamics

        4.3.1. Drivers

        4.3.2. Restraints

        4.3.3. Opportunities

    4.4. Global Oligonucleotide Synthesis Market Analysis and Forecast, 2017–2027

        4.4.1. Market Revenue Projections (US$ Mn)

5. Key Insights

    5.1. Porter’s Five Force Analysis

    5.2. Value Chain Analysis

    5.3. Market Outlook

    5.4. Applications of Oligonucleotides

    5.5. PEST Analysis

    5.6. Pipeline Analysis 

6. Global Oligonucleotide Synthesis Market Analysis and Forecast, by Product Type

    6.1. Introduction & Definition

        6.1.1. Key Findings / Developments

    6.2. Global Oligonucleotide Synthesis Market Value Forecast, by Product Type, 2017–2027

        6.2.1. Reagents & Consumables

        6.2.2. Equipment

        6.2.3. Synthesized oligonucleotides

            6.2.3.1. DNA Oligonucleotides  

            6.2.3.2. RNA Oligonucleotides 

            6.2.3.3. Others

    6.3. Global Oligonucleotide Synthesis Market Attractiveness, by Product Type

7. Global Oligonucleotide Synthesis Market Analysis and Forecast, by Application

    7.1. Introduction & Definition

        7.1.1. Key Findings / Developments

    7.2. Global Oligonucleotide Synthesis Market Value Forecast, by Application, 2017–2027

        7.2.1. Research

            7.2.1.1. Polymerase Chain Reaction 

            7.2.1.2. Next Generation Sequencing 

            7.2.1.3. Others

        7.2.2. Therapeutics 

            7.2.2.1. Antisense Oligonucleotides

            7.2.2.2. Nucleic Acid Aptamers

        7.2.3. Diagnostics

    7.3. Global Oligonucleotide Synthesis Market Attractiveness, by Application

8. Global Oligonucleotide Synthesis Market Analysis and Forecast, by End-user

    8.1. Introduction & Definition

        8.1.1. Key Findings / Developments

    8.2. Global Oligonucleotide Synthesis Market Value Forecast, by End-user, 2017–2027

        8.2.1. Biotechnology & Pharmaceutical Companies 

        8.2.2. Research Institutes  

        8.2.3. Diagnostic Laboratories

9. Global Oligonucleotide Synthesis Market Attractiveness, by End-user

10. Global Oligonucleotide Synthesis Market Analysis and Forecast, by Region

    10.1. Key Findings

    10.2. Global Oligonucleotide Synthesis Market Value Forecast, by Region

        10.2.1. North America 

        10.2.2. Europe 

        10.2.3. Asia Pacific 

        10.2.4. Latin America 

        10.2.5. Middle East & Africa 

    10.3. North America Oligonucleotide Synthesis Market Attractiveness, by Region

11. North America Oligonucleotide Synthesis Market Analysis and Forecast

    11.1. Introduction

        11.1.1. Key Findings

    11.2. North America Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Product Type, 2017–2027

        11.2.1. Reagents & Consumables

        11.2.2. Equipment

        11.2.3. Synthesized oligonucleotides

            11.2.3.1. DNA Oligonucleotides  

            11.2.3.2. RNA Oligonucleotides 

            11.2.3.3. Others

    11.3. North America Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Application, 2017–2027

        11.3.1. Research

            11.3.1.1. Polymerase Chain Reaction 

            11.3.1.2. Next Generation Sequencing 

            11.3.1.3. Others

        11.3.2. Therapeutics 

            11.3.2.1. Antisense Oligonucleotides

            11.3.2.2. Nucleic Acid Aptamers

        11.3.3. Diagnostics

    11.4. North America Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by End-user, 2017–2027

        11.4.1. Biotechnology & Pharmaceutical Companies 

        11.4.2. Research Institutes  

        11.4.3. Diagnostic Laboratories

    11.5. North America Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Country, 2017–2027

        11.5.1. U.S.

        11.5.2. Canada

    11.6. North America Oligonucleotide Synthesis Market Attractiveness Analysis 

        11.6.1. By Product Type

        11.6.2. By Application

        11.6.3. By End-users

        11.6.4. By Country

12. Europe Oligonucleotide Synthesis Market Analysis and Forecast

    12.1. Introduction

        12.1.1. Key Findings

    12.2. Europe Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Product Type, 2017–2027

        12.2.1. Reagents & Consumables

        12.2.2. Equipment

        12.2.3. Synthesized oligonucleotides

            12.2.3.1. DNA Oligonucleotides  

            12.2.3.2. RNA Oligonucleotides 

            12.2.3.3. Others

    12.3. Europe Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Application, 2017–2027

        12.3.1. Research

            12.3.1.1. Polymerase Chain Reaction 

            12.3.1.2. Next Generation Sequencing 

            12.3.1.3. Others

        12.3.2. Therapeutics 

            12.3.2.1. Antisense Oligonucleotides

            12.3.2.2. Nucleic Acid Aptamers

        12.3.3. Diagnostics

    12.4. Europe Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by End-user, 2017–2027

        12.4.1. Biotechnology & Pharmaceutical Companies 

        12.4.2. Research Institutes  

        12.4.3. Diagnostic Laboratories

    12.5. Europe Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Country/Sub-region, 2017–2027

        12.5.1. Germany

        12.5.2. U.K.

        12.5.3. France

        12.5.4. Spain

        12.5.5. Italy

        12.5.6. Rest of Europe 

    12.6. Europe Oligonucleotide Synthesis Market Attractiveness Analysis 

        12.6.1. By Product Type

        12.6.2. By Application

        12.6.3. By End-users

        12.6.4. By Country/Sub-region

13. Asia Pacific Oligonucleotide Synthesis Market Analysis and Forecast

    13.1. Introduction

        13.1.1. Key Findings

    13.2. Asia Pacific Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Product Type, 2017–2027

        13.2.1. Reagents & Consumables

        13.2.2. Equipment

        13.2.3. Synthesized oligonucleotides

            13.2.3.1. DNA Oligonucleotides  

            13.2.3.2. RNA Oligonucleotides 

            13.2.3.3. Others

    13.3. Asia Pacific Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Application, 2017–2027

        13.3.1. Research

            13.3.1.1. Polymerase Chain Reaction 

            13.3.1.2. Next Generation Sequencing 

            13.3.1.3. Others

        13.3.2. Therapeutics 

            13.3.2.1. Antisense Oligonucleotides

            13.3.2.2. Nucleic Acid Aptamers

        13.3.3. Diagnostics

    13.4. Asia Pacific Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by End-user, 2017–2027

        13.4.1. Biotechnology & Pharmaceutical Companies 

        13.4.2. Research Institutes  

        13.4.3. Diagnostic Laboratories

    13.5. Asia Pacific Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Country/Sub-region, 2017–2027

        13.5.1. China

        13.5.2. Japan

        13.5.3. India

        13.5.4. Australia & New Zealand

        13.5.5. Rest of Asia Pacific 

    13.6. Asia Pacific Oligonucleotide Synthesis Market Attractiveness Analysis 

        13.6.1. By Product Type

        13.6.2. By Application

        13.6.3. By End-users

        13.6.4. By Country/Sub-region

14. Latin America Oligonucleotide Synthesis Market Analysis and Forecast

    14.1. Introduction

        14.1.1. Key Findings

    14.2. Latin America Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Product Type, 2017–2027

        14.2.1. Reagents & Consumables

        14.2.2. Equipment

        14.2.3. Synthesized oligonucleotides

            14.2.3.1. DNA Oligonucleotides  

            14.2.3.2. RNA Oligonucleotides 

            14.2.3.3. Others

    14.3. Latin America Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Application, 2017–2027

        14.3.1. Research

            14.3.1.1. Polymerase Chain Reaction 

            14.3.1.2. Next Generation Sequencing 

            14.3.1.3. Others

        14.3.2. Therapeutics 

            14.3.2.1. Antisense Oligonucleotides

            14.3.2.2. Nucleic Acid Aptamers

        14.3.3. Diagnostics

    14.4. Latin America Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by End-user, 2017–2027

        14.4.1. Biotechnology & Pharmaceutical Companies 

        14.4.2. Research Institutes  

        14.4.3. Diagnostic Laboratories

    14.5. Latin America Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Country/Sub-region, 2017–2027

        14.5.1. Brazil

        14.5.2. Mexico

        14.5.3. Rest of Latin America Latin America 

    14.6. Latin America Oligonucleotide Synthesis Market Attractiveness Analysis 

        14.6.1. By Product Type

        14.6.2. By Application

        14.6.3. By End-users

        14.6.4. By Country/Sub-region

15. Middle East & Africa Oligonucleotide Synthesis Market Analysis and Forecast

    15.1. Introduction

        15.1.1. Key Findings

    15.2. Middle East & Africa Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Product Type, 2017–2027

        15.2.1. Reagents & Consumables

        15.2.2. Equipment

        15.2.3. Synthesized oligonucleotides

            15.2.3.1. DNA Oligonucleotides  

            15.2.3.2. RNA Oligonucleotides 

            15.2.3.3. Others

    15.3. Middle East & Africa Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Application, 2017–2027

        15.3.1. Research

            15.3.1.1. Polymerase Chain Reaction 

            15.3.1.2. Next Generation Sequencing 

            15.3.1.3. Others

        15.3.2. Therapeutics 

            15.3.2.1. Antisense Oligonucleotides

            15.3.2.2. Nucleic Acid Aptamers

        15.3.3. Diagnostics

    15.4. Middle East & Africa Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by End-user, 2017–2027

        15.4.1. Biotechnology & Pharmaceutical Companies 

        15.4.2. Research Institutes  

        15.4.3. Diagnostic Laboratories

    15.5. Middle East & Africa Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Country/Sub-region, 2017–2027

        15.5.1. GCC Countries

        15.5.2. South Africa

        15.5.3. Rest of Middle East & Africa 

    15.6. Middle East & Africa Oligonucleotide Synthesis Market Attractiveness Analysis 

        15.6.1. By Product Type

        15.6.2. By Application

        15.6.3. By End-users

        15.6.4. By Country/Sub-region

16. Competition Landscape

    16.1. Market Player - Competition Matrix (by Tier and Size of companies)

    16.2. Market Share / Position Analysis, by Company, 2018

    16.3. Competitive Business Strategies

    16.4. Company Profiles

        16.4.1. GE Healthcare

            16.4.1.1. Company Overview (HQ, Business Segments, Employee Strength)

            16.4.1.2. Financial Overview

            16.4.1.3. Product Portfolio

            16.4.1.4. SWOT Analysis

            16.4.1.5. Strategic Overview

        16.4.2. Thermo Fisher Scientific 

            16.4.2.1. Company Overview (HQ, Business Segments, Employee Strength)

            16.4.2.2. Financial Overview

            16.4.2.3. Product Portfolio

            16.4.2.4. SWOT Analysis

            16.4.2.5. Strategic Overview

        16.4.3. Agilent Technologies, Inc. 

            16.4.3.1. Company Overview (HQ, Business Segments, Employee Strength)

            16.4.3.2. Financial Overview

            16.4.3.3. Product Portfolio

            16.4.3.4. SWOT Analysis

            16.4.3.5. Strategic Overview

        16.4.4. Merck KGaA 

            16.4.4.1. Company Overview (HQ, Business Segments, Employee Strength)

            16.4.4.2. Financial Overview

            16.4.4.3. Product Portfolio

            16.4.4.4. SWOT Analysis

            16.4.4.5. Strategic Overview

        16.4.5. Integrated DNA Technologies, Inc.

            16.4.5.1. Company Overview (HQ, Business Segments, Employee Strength)

            16.4.5.2. Financial Overview

            16.4.5.3. Product Portfolio

            16.4.5.4. SWOT Analysis

            16.4.5.5. Strategic Overview

        16.4.6. Kaneka Eurogentec S.A. (Kaneka Corporation) 

            16.4.6.1. Company Overview (HQ, Business Segments, Employee Strength)

            16.4.6.2. Financial Overview

            16.4.6.3. Product Portfolio

            16.4.6.4. SWOT Analysis

            16.4.6.5. Strategic Overview 

        16.4.7. TriLink BioTechnologies,LLC  (Maravai Life Sciences) 

            16.4.7.1. Company Overview (HQ, Business Segments, Employee Strength)

            16.4.7.2. Financial Overview

            16.4.7.3. Product Portfolio

            16.4.7.4. SWOT Analysis

            16.4.7.5. Strategic Overview

        16.4.8. BioAutomation 

            16.4.8.1. Company Overview (HQ, Business Segments, Employee Strength)

            16.4.8.2. Financial Overview

            16.4.8.3. Product Portfolio

            16.4.8.4. SWOT Analysis

            16.4.8.5. Strategic Overview

        16.4.9. ATDBio Ltd.

            16.4.9.1. Company Overview (HQ, Business Segments, Employee Strength)

            16.4.9.2. Financial Overview

            16.4.9.3. Product Portfolio

            16.4.9.4. SWOT Analysis

            16.4.9.5. Strategic Overview

        16.4.10. Gene Design, Inc. 

            16.4.10.1. Company Overview (HQ, Business Segments, Employee Strength)

            16.4.10.2. Financial Overview

            16.4.10.3. Product Portfolio

            16.4.10.4. SWOT Analysis

            16.4.10.5. Strategic Overview

        16.4.11. Eurofins Genomics 

            16.4.11.1. Company Overview (HQ, Business Segments, Employee Strength)

            16.4.11.2. Financial Overview

            16.4.11.3. Product Portfolio

            16.4.11.4. SWOT Analysis

            16.4.11.5. Strategic Overview

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