Oligonucleotide Synthesis Market (Product - Reagents & Consumables, Equipment, and Synthesized Oligonucleotides (DNA Oligonucleotides and RNA Oligonucleotides); Application - Research (Polymerase Chain Reaction and Next Generation Sequencing), Therapeutics (Antisense Oligonucleotides, and Nucleic Acid Aptamers), and Diagnostics; End User - Biotechnology & Pharmaceutical Companies, Research Institutes, and Diagnostic Laboratories) - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2019 - 2030
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Description
The global oligonucleotide synthesis market for the historical period 2017–2018 and forecast period 2019–2027, Increasing use of synthesized oligonucleotides in diagnostics and research applications, and Technological advancements in synthetic chemistry are projected to drive the global oligonucleotide synthesis market during the forecast period
According to the report, the global oligonucleotide synthesis market was valued at US$ 1,966.2 Mn in 2018 and is anticipated to expand at a CAGR of 9.5% from 2019 to 2030
Technological advancements in synthetic chemistry to Drive Global Oligonucleotide Synthesis: Key Drivers
The advances in the technological development of organic molecules are expected to drive the growth of the oligonucleotide synthesis market
The advanced synthesis of oligonucleotides provides longer oligos with better sequence fidelity and higher purity that can be used in a number of molecular biology applications
Various pharmaceutical and biotechnology companies are continuously working on developing newer and advanced methods in synthetic chemistry
For instance, Integrated DNA Technologies, leader of synthesized oligonucleotides has developed various pioneered methods to synthesize oligonucleotides of extreme lengths. The company has developed oligonucleotides up to 200 base length which is used with mass spectrometry for the manufacture of mini-genes.
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Increasing use of Synthesized Oligonucleotides in Diagnostics and Research Applications Boost Market Growth
Oligonucleotides have a wide range of applications in areas such as molecular biology, biotechnology, and diagnosis
Natural oligonucleotides have been extensively used for the selection and determination of DNA sequences (hybridization probes or affinity purification), gene construction, and site-directed mutagenesis
They constitute the basic reagents for PCR technologies. They are also used to selectively inhibit gene expression in in vitro studies for diagnostic purpose and more recently, their ability to interact with proteins has generated immense opportunity for therapeutic use.
Along with diagnostics, they are widely used in research studies. Combinatorial technology is another research area where oligonucleotides and their analogs are extensively employed.
Limitations in the Synthesis of Oligonucleotides to Hamper Market
An oligonucleotide is a single-stranded chain consisting of a number of nucleoside units linked together by phosphodiester bridges
Mostly in oligonucleotide synthesis, phosphodiesters are formed between a 3’-hydroxyl group bearing a phosphate derivative and a 5’-hydroxyl group of another nucleoside
The occurrence of side reactions sets practical limits for the length of synthetic DNA oligonucleotides (up to about 200 nucleotide residues) because the number of errors accumulates with the length of the oligonucleotide being synthesized
To synthesize RNA with longer nucleotides base, that is more than 50 nucleotides is very complex and difficult to prepare
But, most biologically important RNA molecules such as ribozymes, aptamers, and riboswitches are significantly longer than 50 nucleotides, so new approaches for the synthesis of RNA analogs are urgently required
Global Oligonucleotide Synthesis Market: Competitive Landscape
This report profiles major players in the global oligonucleotide synthesis market based on various attributes such as company overview, financial overview, product portfolio, business strategies, and recent developments
The global oligonucleotide synthesis market is highly fragmented, with the presence of a number of international as well as regional players
Leading players operating in the global Oligonucleotide Synthesis market are
- GE Healthcare
- Thermo Fischer Scientific
- Agilent Technologies, Inc.
- Merck KGaA
- Integrated DNA Technologies, Inc.
- Kaneka Eurogentec S.A
- BioAutomation
- Gene Design, Inc.
- Eurofins Genomics
- ATDBio, Ltd..
Global Oligonucleotide Synthesis Market: Key Developments
Key players in the global oligonucleotide synthesis market are engaged in regulatory approvals, technologically advanced products, launch of new products, and acquisition & collaborative agreements with other companies. These strategies are likely to fuel the growth of the global oligonucleotide synthesis market. A few expansion strategies adopted by players operating in the global oligonucleotide Synthesis market are:
In May 2017, GE Healthcare announced the launch of its Superdex 30 Increase, a new generation column resin for small-scale preparative purification and analysis, adding another product to the already existing wide portfolio of Superdex Increase family of SEC columns.
The report on the global oligonucleotide synthesis market discussed individual strategies, followed by company profiles of manufacturers of oligonucleotide synthesis. The competitive landscape section has been included in the report to provide readers with a dashboard view and a company market share analysis of key players operating in the global oligonucleotide synthesis market.
Key Questions Answered in Global Oligonucleotide Synthesis Market Report
- What is the scope of growth of product companies in the global oligonucleotide synthesis market?
- What will be the Y-o-Y growth of the global oligonucleotide synthesis market between 2019 and 2027?
- What is the influence of changing trends in technologies on the global oligonucleotide synthesis market?
- Will North America continue to be the most profitable market for oligonucleotide synthesis providers?
- Which factors are anticipated to hamper the growth of the global oligonucleotide synthesis market during the forecast period?
- Which are the leading companies in the global oligonucleotide synthesis market?
Global Oligonucleotide Synthesis Market – Segmentation
Product Product Type
- Reagents & Consumables
- Equipment
- Synthesized Oligonucleotides
- DNA
- RNA
- Others
Applications
- Research
- Polymerase Chain Reaction
- Next Generation Sequencing
- Others
- Therapeutics
- Antisense Oligonucleotides
- Nucleic Acid Aptamers
- Diagnostic
End User
- Biotech & Pharma Companies
- Research Inst.
- Diagnostic Labs
Region
- North America
- Europe
- Asia Pacific
- Latin America
- MEA
TABLE OF CONTENT
1. Preface
1.1. Market Definition and Scope
1.2. Market Segmentation
1.3. Key Research Objectives
1.4. Research Highlights
2. Assumptions and Research Methodology
3. Executive Summary: Global Oligonucleotide Synthesis Market
4. Market Overview
4.1. Introduction
4.1.1. Product Type Definition
4.1.2. Industry Evolution / Developments
4.2. Overview
4.3. Market Dynamics
4.3.1. Drivers
4.3.2. Restraints
4.3.3. Opportunities
4.4. Global Oligonucleotide Synthesis Market Analysis and Forecast, 2017–2027
4.4.1. Market Revenue Projections (US$ Mn)
5. Key Insights
5.1. Porter’s Five Force Analysis
5.2. Value Chain Analysis
5.3. Market Outlook
5.4. Applications of Oligonucleotides
5.5. PEST Analysis
5.6. Pipeline Analysis
6. Global Oligonucleotide Synthesis Market Analysis and Forecast, by Product Type
6.1. Introduction & Definition
6.1.1. Key Findings / Developments
6.2. Global Oligonucleotide Synthesis Market Value Forecast, by Product Type, 2017–2027
6.2.1. Reagents & Consumables
6.2.2. Equipment
6.2.3. Synthesized oligonucleotides
6.2.3.1. DNA Oligonucleotides
6.2.3.2. RNA Oligonucleotides
6.2.3.3. Others
6.3. Global Oligonucleotide Synthesis Market Attractiveness, by Product Type
7. Global Oligonucleotide Synthesis Market Analysis and Forecast, by Application
7.1. Introduction & Definition
7.1.1. Key Findings / Developments
7.2. Global Oligonucleotide Synthesis Market Value Forecast, by Application, 2017–2027
7.2.1. Research
7.2.1.1. Polymerase Chain Reaction
7.2.1.2. Next Generation Sequencing
7.2.1.3. Others
7.2.2. Therapeutics
7.2.2.1. Antisense Oligonucleotides
7.2.2.2. Nucleic Acid Aptamers
7.2.3. Diagnostics
7.3. Global Oligonucleotide Synthesis Market Attractiveness, by Application
8. Global Oligonucleotide Synthesis Market Analysis and Forecast, by End-user
8.1. Introduction & Definition
8.1.1. Key Findings / Developments
8.2. Global Oligonucleotide Synthesis Market Value Forecast, by End-user, 2017–2027
8.2.1. Biotechnology & Pharmaceutical Companies
8.2.2. Research Institutes
8.2.3. Diagnostic Laboratories
9. Global Oligonucleotide Synthesis Market Attractiveness, by End-user
10. Global Oligonucleotide Synthesis Market Analysis and Forecast, by Region
10.1. Key Findings
10.2. Global Oligonucleotide Synthesis Market Value Forecast, by Region
10.2.1. North America
10.2.2. Europe
10.2.3. Asia Pacific
10.2.4. Latin America
10.2.5. Middle East & Africa
10.3. North America Oligonucleotide Synthesis Market Attractiveness, by Region
11. North America Oligonucleotide Synthesis Market Analysis and Forecast
11.1. Introduction
11.1.1. Key Findings
11.2. North America Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Product Type, 2017–2027
11.2.1. Reagents & Consumables
11.2.2. Equipment
11.2.3. Synthesized oligonucleotides
11.2.3.1. DNA Oligonucleotides
11.2.3.2. RNA Oligonucleotides
11.2.3.3. Others
11.3. North America Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Application, 2017–2027
11.3.1. Research
11.3.1.1. Polymerase Chain Reaction
11.3.1.2. Next Generation Sequencing
11.3.1.3. Others
11.3.2. Therapeutics
11.3.2.1. Antisense Oligonucleotides
11.3.2.2. Nucleic Acid Aptamers
11.3.3. Diagnostics
11.4. North America Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by End-user, 2017–2027
11.4.1. Biotechnology & Pharmaceutical Companies
11.4.2. Research Institutes
11.4.3. Diagnostic Laboratories
11.5. North America Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Country, 2017–2027
11.5.1. U.S.
11.5.2. Canada
11.6. North America Oligonucleotide Synthesis Market Attractiveness Analysis
11.6.1. By Product Type
11.6.2. By Application
11.6.3. By End-users
11.6.4. By Country
12. Europe Oligonucleotide Synthesis Market Analysis and Forecast
12.1. Introduction
12.1.1. Key Findings
12.2. Europe Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Product Type, 2017–2027
12.2.1. Reagents & Consumables
12.2.2. Equipment
12.2.3. Synthesized oligonucleotides
12.2.3.1. DNA Oligonucleotides
12.2.3.2. RNA Oligonucleotides
12.2.3.3. Others
12.3. Europe Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Application, 2017–2027
12.3.1. Research
12.3.1.1. Polymerase Chain Reaction
12.3.1.2. Next Generation Sequencing
12.3.1.3. Others
12.3.2. Therapeutics
12.3.2.1. Antisense Oligonucleotides
12.3.2.2. Nucleic Acid Aptamers
12.3.3. Diagnostics
12.4. Europe Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by End-user, 2017–2027
12.4.1. Biotechnology & Pharmaceutical Companies
12.4.2. Research Institutes
12.4.3. Diagnostic Laboratories
12.5. Europe Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Country/Sub-region, 2017–2027
12.5.1. Germany
12.5.2. U.K.
12.5.3. France
12.5.4. Spain
12.5.5. Italy
12.5.6. Rest of Europe
12.6. Europe Oligonucleotide Synthesis Market Attractiveness Analysis
12.6.1. By Product Type
12.6.2. By Application
12.6.3. By End-users
12.6.4. By Country/Sub-region
13. Asia Pacific Oligonucleotide Synthesis Market Analysis and Forecast
13.1. Introduction
13.1.1. Key Findings
13.2. Asia Pacific Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Product Type, 2017–2027
13.2.1. Reagents & Consumables
13.2.2. Equipment
13.2.3. Synthesized oligonucleotides
13.2.3.1. DNA Oligonucleotides
13.2.3.2. RNA Oligonucleotides
13.2.3.3. Others
13.3. Asia Pacific Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Application, 2017–2027
13.3.1. Research
13.3.1.1. Polymerase Chain Reaction
13.3.1.2. Next Generation Sequencing
13.3.1.3. Others
13.3.2. Therapeutics
13.3.2.1. Antisense Oligonucleotides
13.3.2.2. Nucleic Acid Aptamers
13.3.3. Diagnostics
13.4. Asia Pacific Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by End-user, 2017–2027
13.4.1. Biotechnology & Pharmaceutical Companies
13.4.2. Research Institutes
13.4.3. Diagnostic Laboratories
13.5. Asia Pacific Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Country/Sub-region, 2017–2027
13.5.1. China
13.5.2. Japan
13.5.3. India
13.5.4. Australia & New Zealand
13.5.5. Rest of Asia Pacific
13.6. Asia Pacific Oligonucleotide Synthesis Market Attractiveness Analysis
13.6.1. By Product Type
13.6.2. By Application
13.6.3. By End-users
13.6.4. By Country/Sub-region
14. Latin America Oligonucleotide Synthesis Market Analysis and Forecast
14.1. Introduction
14.1.1. Key Findings
14.2. Latin America Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Product Type, 2017–2027
14.2.1. Reagents & Consumables
14.2.2. Equipment
14.2.3. Synthesized oligonucleotides
14.2.3.1. DNA Oligonucleotides
14.2.3.2. RNA Oligonucleotides
14.2.3.3. Others
14.3. Latin America Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Application, 2017–2027
14.3.1. Research
14.3.1.1. Polymerase Chain Reaction
14.3.1.2. Next Generation Sequencing
14.3.1.3. Others
14.3.2. Therapeutics
14.3.2.1. Antisense Oligonucleotides
14.3.2.2. Nucleic Acid Aptamers
14.3.3. Diagnostics
14.4. Latin America Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by End-user, 2017–2027
14.4.1. Biotechnology & Pharmaceutical Companies
14.4.2. Research Institutes
14.4.3. Diagnostic Laboratories
14.5. Latin America Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Country/Sub-region, 2017–2027
14.5.1. Brazil
14.5.2. Mexico
14.5.3. Rest of Latin America Latin America
14.6. Latin America Oligonucleotide Synthesis Market Attractiveness Analysis
14.6.1. By Product Type
14.6.2. By Application
14.6.3. By End-users
14.6.4. By Country/Sub-region
15. Middle East & Africa Oligonucleotide Synthesis Market Analysis and Forecast
15.1. Introduction
15.1.1. Key Findings
15.2. Middle East & Africa Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Product Type, 2017–2027
15.2.1. Reagents & Consumables
15.2.2. Equipment
15.2.3. Synthesized oligonucleotides
15.2.3.1. DNA Oligonucleotides
15.2.3.2. RNA Oligonucleotides
15.2.3.3. Others
15.3. Middle East & Africa Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Application, 2017–2027
15.3.1. Research
15.3.1.1. Polymerase Chain Reaction
15.3.1.2. Next Generation Sequencing
15.3.1.3. Others
15.3.2. Therapeutics
15.3.2.1. Antisense Oligonucleotides
15.3.2.2. Nucleic Acid Aptamers
15.3.3. Diagnostics
15.4. Middle East & Africa Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by End-user, 2017–2027
15.4.1. Biotechnology & Pharmaceutical Companies
15.4.2. Research Institutes
15.4.3. Diagnostic Laboratories
15.5. Middle East & Africa Oligonucleotide Synthesis Market Value (US$ Mn) Forecast, by Country/Sub-region, 2017–2027
15.5.1. GCC Countries
15.5.2. South Africa
15.5.3. Rest of Middle East & Africa
15.6. Middle East & Africa Oligonucleotide Synthesis Market Attractiveness Analysis
15.6.1. By Product Type
15.6.2. By Application
15.6.3. By End-users
15.6.4. By Country/Sub-region
16. Competition Landscape
16.1. Market Player - Competition Matrix (by Tier and Size of companies)
16.2. Market Share / Position Analysis, by Company, 2018
16.3. Competitive Business Strategies
16.4. Company Profiles
16.4.1. GE Healthcare
16.4.1.1. Company Overview (HQ, Business Segments, Employee Strength)
16.4.1.2. Financial Overview
16.4.1.3. Product Portfolio
16.4.1.4. SWOT Analysis
16.4.1.5. Strategic Overview
16.4.2. Thermo Fisher Scientific
16.4.2.1. Company Overview (HQ, Business Segments, Employee Strength)
16.4.2.2. Financial Overview
16.4.2.3. Product Portfolio
16.4.2.4. SWOT Analysis
16.4.2.5. Strategic Overview
16.4.3. Agilent Technologies, Inc.
16.4.3.1. Company Overview (HQ, Business Segments, Employee Strength)
16.4.3.2. Financial Overview
16.4.3.3. Product Portfolio
16.4.3.4. SWOT Analysis
16.4.3.5. Strategic Overview
16.4.4. Merck KGaA
16.4.4.1. Company Overview (HQ, Business Segments, Employee Strength)
16.4.4.2. Financial Overview
16.4.4.3. Product Portfolio
16.4.4.4. SWOT Analysis
16.4.4.5. Strategic Overview
16.4.5. Integrated DNA Technologies, Inc.
16.4.5.1. Company Overview (HQ, Business Segments, Employee Strength)
16.4.5.2. Financial Overview
16.4.5.3. Product Portfolio
16.4.5.4. SWOT Analysis
16.4.5.5. Strategic Overview
16.4.6. Kaneka Eurogentec S.A. (Kaneka Corporation)
16.4.6.1. Company Overview (HQ, Business Segments, Employee Strength)
16.4.6.2. Financial Overview
16.4.6.3. Product Portfolio
16.4.6.4. SWOT Analysis
16.4.6.5. Strategic Overview
16.4.7. TriLink BioTechnologies,LLC (Maravai Life Sciences)
16.4.7.1. Company Overview (HQ, Business Segments, Employee Strength)
16.4.7.2. Financial Overview
16.4.7.3. Product Portfolio
16.4.7.4. SWOT Analysis
16.4.7.5. Strategic Overview
16.4.8. BioAutomation
16.4.8.1. Company Overview (HQ, Business Segments, Employee Strength)
16.4.8.2. Financial Overview
16.4.8.3. Product Portfolio
16.4.8.4. SWOT Analysis
16.4.8.5. Strategic Overview
16.4.9. ATDBio Ltd.
16.4.9.1. Company Overview (HQ, Business Segments, Employee Strength)
16.4.9.2. Financial Overview
16.4.9.3. Product Portfolio
16.4.9.4. SWOT Analysis
16.4.9.5. Strategic Overview
16.4.10. Gene Design, Inc.
16.4.10.1. Company Overview (HQ, Business Segments, Employee Strength)
16.4.10.2. Financial Overview
16.4.10.3. Product Portfolio
16.4.10.4. SWOT Analysis
16.4.10.5. Strategic Overview
16.4.11. Eurofins Genomics
16.4.11.1. Company Overview (HQ, Business Segments, Employee Strength)
16.4.11.2. Financial Overview
16.4.11.3. Product Portfolio
16.4.11.4. SWOT Analysis
16.4.11.5. Strategic Overview