RNA Purification Kits Help Isolate SARS-CoV-2 Using Spin Column Chromatography
Virus purification activities are surging with full throttle amidst the ongoing COVID-19 (coronavirus) pandemic. Unprecedented demand for vaccines and drugs is creating value-grab opportunities for companies in the virus purification kits market. As such, RNA purification kits are being highly publicized for conducting total isolation of SARS-CoV-2. Researchers and scientists are preferring purification based on spin column chromatography using a proprietary resin as the separation matrix.
The demand for virus purification kits is surging amidst the COVID-19 pandemic, since scientists are increasing efforts to yield purified RNA of the highest integrity that can be useful in downstream applications. Procedures such as reagent preparation, lysate preparation, and RNA purification, among others, are anticipated to intensify in the upcoming months due to the growing demand for vaccines. This is projected to drive the virus purification kits market during the forecast period.
Higher Yields in Recovery of Particles Preferred by Researchers and Academicians
Fast and safe virus purification kits are becoming increasingly popular in the healthcare landscape. The U.S. multinational pharmaceutical company Merck is increasing its production capacities for Millipore’s fast-trap adenovirus and lentivirus purification and concentration kits that are emerging as a fast and safe alternative to conventional kits. Companies in the virus purification kits market are focusing on high recovery of viable viral particles with good purity.
Time efficiency and higher yields in recovery of particles are preferred in virus purification kits. There is a growing demand for kits that eliminate messy purification steps and eliminate the need for expensive equipment. As such, companies in the virus purification kits market are developing close vacuum devices that eliminate risks of potential spills and meet the convenience of researchers and healthcare professionals. Advanced virus purification kits are solving issues of labor intensive procedures in laboratory and academic research settings.
Adenovirus Purification Kits Eliminate Need for Time-consuming Ultracentrifugation Procedures
The virus purification kits market is expected to advance at a striking CAGR of ~11% during the assessment period. This can be attributed to innovations in kits that help deliver fast and efficient purification of recombinant virus. For instance, BioVision-a supplier of high quality assay kits has a wide product portfolio in adenovirus, lentivirus, and retrovirus purification kits. As such, adenovirus purification kits are anticipated to dominate the highest revenue share among all virus types in the virus purification kits market.
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Manufacturers are increasing the availability of ready-to-use reagents in virus purification kits to make the procedure of particle recovery simple, easy, and convenient. They are developing kits that eliminate the need for ultracentrifugation, since this procedure is time consuming and limited to the amount of cell lysate to be processed.
Single-use Membrane Chromatography Reduces Manufacturing Costs of Vaccines
The virus purification kits market is expected to reach US$ 3.2 Bn by the end of 2030. However, high costs involving complex procedures for vaccine production and gene therapy pose as barriers for market growth. Hence, manufacturers are using single-use membrane chromatography to bolster productivity levels and reduce manufacturing costs. For instance, the Natrix® single-use membrane chromatography procedure is highly sought after for high binding and short residence times in developing viral vectors for gene therapy.
In order to test new constructs, parallel and fast purification of different adenoviruses is essential. In order to achieve this, companies are introducing simple and affordable spin column based purification kits. On the other hand, researchers and scientists are conducting virus purification using the membrane adsorber technology.
Scientists are elucidating the dynamics of novel coronavirus SARS-CoV-2 lifecycle using RNA purification kits in order to develop and design diagnostics and antiviral therapies. Magnetic beads-based kits help to accelerate purification speeds. However, lack of effective process validation strategies for highly complex biomolecules poses as a challenge for manufacturers. Hence, manufacturers in the virus purification kits market should understand the regulatory and scientific requirements before commercializing their products. They should introduce virus purification kits with easy membrane-based methods to accelerate purification procedures in large-scale laboratory settings. Manufacturers should increase their production capabilities to design pump driven kits for the purification of larger volumes of virus particles.
Virus Purification Kits Market: Overview
Virus purification is a process that involves separation, isolation, and purification of a virus from cell organelles and host tissues
Virus purification kits comprise all tools and components required to accommodate complete workflow of the virus purification procedure. These kits have replaced the lengthy and time-consuming traditional procedure of virus purification.
Ultracentrifugation is a technology that is utilized to separate macromolecules into different component parts based on the size of the particles in the mixture. It is a traditional technology used in the virus purification kits market.
Different kinds of particles such as viruses, bacteria, and organelles have different sizes and are driven away from the centrifugal axis in the equipment to different locations accordingly
Chromatography is a technology that is useful for purifying both enveloped and non-enveloped viruses, particularly through column chromatography
Most viruses are enveloped, which means that they have their nucleic acid (DNA and RNA) covered in a protein cover called the capsid, which further has a membrane envelope on it
Virus Purification Kits: Market Drivers
Rise in research funding by public and private players and higher yield of virus particles received with the help of virus purification kits are major driving factors driving the global virus purification kits market
For instance, Millipore (Merck KGaA) offers fast-trap adenovirus and lentivirus purification and concentration kits that provide a fast, safe, and easy alternative to viral purification. It offers comparatively faster processing time and higher recovery of adenovirus and lentivirus with 70% and 51%, respectively.
Increase in support from government bodies for biotechnology and pharmaceutical industries is also fueling the global virus purification kits market
Consistent expansion of biopharmaceutical and biotechnology industries boosts the global virus purification kits market
Market Segmentation: Virus Purification Kits Market
Based on technology, the global virus purification kits market has been segmented into ultracentrifugation, chromatography, nanofiltration, and others
In terms of virus type, the global virus purification kits market has been divided into adenovirus, lentivirus, retrovirus, and others
Based on end user, the global virus purification kits market has been segmented into academic & research institutes, biopharmaceutical & biotechnology companies, contract research organizations(CROs), and others
Each of the virus purification kits market segments has been analyzed in detail for market trends, recent trends and developments, drivers, restraints, opportunities, and useful insights
The virus purification kits market report provides current and future values (US$ Mn) for each these segments for the period from 2018 to 2030, considering 2019 as the base year. The compound annual growth rate (% CAGR) has been provided for each segment and virus purification kits market from 2020 to 2030, along with virus purification kits market size estimations.
Regional Overview: Virus Purification Kits Market
In terms of region, the global virus purification kits market has been divided into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. The regions have been further divided into major countries and sub-regions.
North America dominated the global virus purification kits market in 2019. It is estimated maintain its dominant position during the forecast period.
The current and future virus purification kits market sizes in terms of value (US$ Mn) of these regional markets and their major countries have been provided in the report for the period from 2018 to 2030, with their CAGRs for the period from 2020 to 2030
The study also offers a list of recommendations, highlights, and useful insights of the global virus purification kits market, which would help new companies willing to enter the market and existing companies to increase global virus purification kits market shares, and help in the decision-making process
The virus purification kits market report concludes with the company profiles section that includes key information about the major players in the virus purification kits market
Key players analyzed in virus purification kits market report are
Each of these players has been profiled in the global virus purification kits market report based on parameters such as company overview, financial overview, business strategies, product portfolio, business segments, and recent developments
Key Questions Answered in Virus Purification Kits Market Report
Virus Purification Kits Market – Segmentation